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- W2040277195 abstract "Background:Myocardial perfusion scintigraphy with intravenous adenosine has proved efficacy for the diagnosis and risk stratification of coronary artery disease. To determine the safety of ade- nosine infusion in conjunction with radionuclide imaging, we evaluated pro-spectively 1,093 patients who underwent myocardial perfusion study. Methods:Informations on safety and adverse events during and immediately after adenosine in- fusion were collected and statistical analysis was performed. Results:The adverse events were reported in 730 patients(66.8%, but no death or myocardial infarction. These adverse events were well tolerated and no prolonged effect was noted. Chest pain occurred in 223 patients(20.4% and facial flushing and dyspnea were reported by 246 pa- tients(22.5% and 253 patients(23.1%, respectively. ECG changes, such as mild arrhythmia, ST depression and AV block were checked in 230 patients(21.0%. The infusion was prematurely terminated in 32 patients(2.9%, due to severe chest pain, severe brochospasm, or third degree AV block. Higher frequency of chest pain was reported in women compare to men(p<0.05, and ST se- gment depression was more frequent in patients with abnormal myocardial perfusion scintigraphic findings(p<0.05." @default.
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- W2040277195 date "1997-01-01" @default.
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- W2040277195 title "Safety Profile of Adenosine Myocardial Perfusion Imaging" @default.
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- W2040277195 doi "https://doi.org/10.4070/kcj.1997.27.2.189" @default.
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