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- W2040293208 abstract "PurposeTo investigate the characteristics of the aetiologies of convulsive status epilepticus (CSE) in Western China and to identify the relationships of these aetiologies with the prognoses.MethodsConsecutive registration and prospective observation of 258 cases of CSE in the Sichuan Epilepsy Center were performed from 1996 to 2010 to study the aetiology of CSE. The relationships of the aetiologies with the demographics, outcomes and complications of CSE were analysed using a logistic regression model.ResultsThe mean age was 37.6 ± 20.21 years. The majority of the CSE (62.4%) cases were acute symptomatic cases, and the primary cause was central nervous system (CNS) infection (33.7%). Histories of epilepsy were present in 51.9% of the patients. Pre-existing epilepsy occurred due to discontinuation or reduction of antiepileptic drugs (AEDs) in 31.3% of the CSE patients. Anoxia/poisoning (p < 0.05, OR 8.0, 95% CI 1.34–47.77) was an independent predictor of mortality. CNS infections (p < 0.001, OR 8.99, 95% CI 3.52–22.92), cerebrovascular diseases (p =0.001, OR 6.75, 95% CI 2.11–21.61) and anoxia/poisoning (p < 0.01, OR 7.64, 95% CI 1.93–30.21) were the major risk factors for complications associated with CSE.Conclusions(1) Compared to developed countries, CNS infections seemed to be more likely to be the cause of CSE in developing countries. (2) Noncompliance with AEDs among patients with epilepsy was a prominent and avoidable trigger of CSE." @default.
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- W2040293208 date "2014-10-01" @default.
- W2040293208 modified "2023-09-30" @default.
- W2040293208 title "The aetiology of convulsive status epilepticus: A study of 258 cases in Western China" @default.
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- W2040293208 doi "https://doi.org/10.1016/j.seizure.2014.05.015" @default.
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