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• W2040299169 abstract "Effects of taurine (2-aminoethanesulfonic acid) on the uptake and release of 14 C-acctylcholine ( 14 C-ACh) and 3 H-norepinephrine ( 3 H-NE) in the superior cervical ganglion and cerebral cortex of the rat were studied. Taurine suppressed high potassium evoked release of 14 C-ACh and 3 H-NE from the rat superior cervical ganglia and cerebral cortical slices, while the drug did not modify per se the uptake and unstimulated (spontaneous) release of 14 C-ACh and 3 H-NE in these tissues. Furthermore, taurine inhibited the release of 3 H-NE from the crude synaptosomal (P2) fraction of the rat brain without affecting the uptake. These results suggest that taurine may act as a modulator of neuronal activity, possibly by stabilizing excitable membrane and by suppressing the release of neurotransmitter at synapses." @default.
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• W2040299169 date "1978-01-01" @default.
• W2040299169 modified "2023-10-17" @default.
• W2040299169 title "A MODULATING ROLE OF TAURINE ON RELEASE OF ACETYLCHOLINE AND NOREPINEPHRINE FROM NEURONAL TISSUES" @default.
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• W2040299169 doi "https://doi.org/10.1254/jjp.28.259" @default.
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