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- W2040304617 endingPage "3128" @default.
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- W2040304617 abstract "Dry eye disease is one of the most commonly encountered conditions in eye care, and inflammation is a frequent finding. Ciclosporin has long been used systemically to decrease the deleterious effects of inflammation. Ciclosporin is a calcineurin inhibitor that acts by primarily blocking the action of T cells, decreasing the release of pro-inflammatory cytokines, and preventing the apoptosis of goblet cells.This article reviews the clinical trials and safety profile of an ophthalmic preparation of ciclosporin in the treatment of dry eye.Clinical trials have demonstrated that ciclosporin minimizes the signs and symptoms of dry eye disease and is not associated with any significant systemic or ocular adverse reaction." @default.
- W2040304617 created "2016-06-24" @default.
- W2040304617 creator A5053426776 @default.
- W2040304617 date "2008-11-12" @default.
- W2040304617 modified "2023-10-14" @default.
- W2040304617 title "Ciclosporin use in dry eye disease patients" @default.
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- W2040304617 doi "https://doi.org/10.1517/14656560802500613" @default.
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