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• W2040317213 abstract "To investigate the involvement of central or peripheral catecholaminergic systems in the MK-801-induced increase in plasma corticosterone and interleukin-6 levels, we pretreated mice either intracerebroventricularly (i.c.v.) or intraperitoneally (i.p.) with 6-hydroxydopamine (6-OHDA) which depletes catecholamines. Pretreatment of animals with 6-OHDA (50 microg i.c.v. or 100 mg/kg i.p.) significantly enhanced the MK-801 (1 microg i.c.v.)-induced increase in plasma corticosterone level. On the other hand, pretreatment of mice with 6-OHDA (50 microg i.c.v. or 100 mg/kg i.p.) did not affect the MK-801 (1 microg i.c.v.)-induced increase in plasma IL-6 level. These results suggest that central and peripheral catecholaminergic systems are involved in the suppressive regulation of MK-801-induced plasma corticosterone level." @default.
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• W2040317213 date "2009-02-01" @default.
• W2040317213 modified "2023-10-18" @default.
• W2040317213 title "Central or peripheral norepinephrine depletion enhances MK-801-induced plasma corticosterone level in mice" @default.
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• W2040317213 doi "https://doi.org/10.1016/j.pnpbp.2008.10.008" @default.
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