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- W2040326777 abstract "The discovery of cortisone and corticotropin (ACTH) raised considerable hope that the therapy for the rheumatoid state was at hand. An evaluation of the results, however, particularly after prolonged use, is indicative that there is much to be desired. Although the initial improvement is excellent in all but a few patients, the overall effectiveness is disappointing. When the results are analyzed in terms of the therapeutic criteria of the American Rheumatism Association, 1 functional improvement is very good but the degree of improvement in terms of rheumatoid activity is usually grade 2 (major) or 3 (minor) and rarely grade 1 (complete remission). In view of the high relapse rate, severe withdrawal syndrome, and toxicity with prolonged use, Freyberg and associates 2 have recently indicated that they are concerned with the question: Will treatment with cortisone be worth while for this patient? Therefore, the therapeutic measures available for the treatment of" @default.
- W2040326777 created "2016-06-24" @default.
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- W2040326777 date "1953-07-11" @default.
- W2040326777 modified "2023-09-27" @default.
- W2040326777 title "TREATMENT OF RHEUMATOID ARTHRITIS WITH AUROTHIOGLYCANIDE (LAURON)" @default.
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- W2040326777 doi "https://doi.org/10.1001/jama.1953.03690110027009" @default.
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