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- W2040347617 abstract "Abstract Heats of adsorption measured by flow microcalorimetry (FMC) were used to understand the energetics of biomolecule adsorption on mesostructured cellular foam (MCF) silica. Tryptophan (Trp), lysozyme (LYS), and bovine serum albumin (BSA) were used as probe molecules. The FMC results confirmed that attractive interactions (both electrostatic and van der Walls interactions) between the biomolecules and acid-washed MCF silica were the driving force for adsorption, even when the protein (BSA) and the surface were both negatively charged and repulsion interactions might be expected. Multiple exothermic events occurred, possibly because of multipoint interactions between biomolecules and MCF silica resulting from multiple binding sites on the biomolecule and a curved pore structure. Interestingly, the magnitude of the enthalpy of adsorption (Δ H Total ) increased with increasing biomolecule size at pH 5.2; the number of exothermic peaks corresponded to the number of binding regions on the biomolecule. In addition, standard Gibbs energies of adsorption (Δ G °) and entropy of adsorption (Δ S °) were calculated from batch adsorption isotherms and the measured enthalpy of adsorption. BSA adsorption energetics were significantly affected by changing the pH from 4 to 5.2. This effect was attributed to a dramatic conformational change of BSA as a function of pH. The energetics of adsorption provide invaluable insight into the mechanism biomolecule adsorption." @default.
- W2040347617 created "2016-06-24" @default.
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- W2040347617 date "2013-04-01" @default.
- W2040347617 modified "2023-09-23" @default.
- W2040347617 title "Energetics of biomolecule adsorption on mesostructured cellular foam silica" @default.
- W2040347617 cites W1617855752 @default.
- W2040347617 cites W1879428958 @default.
- W2040347617 cites W1963690403 @default.
- W2040347617 cites W1964311497 @default.
- W2040347617 cites W1967287809 @default.
- W2040347617 cites W1971028753 @default.
- W2040347617 cites W1976685837 @default.
- W2040347617 cites W1976836668 @default.
- W2040347617 cites W1977870437 @default.
- W2040347617 cites W1980619521 @default.
- W2040347617 cites W1983189420 @default.
- W2040347617 cites W1985474734 @default.
- W2040347617 cites W1985676128 @default.
- W2040347617 cites W1988654845 @default.
- W2040347617 cites W1988902281 @default.
- W2040347617 cites W1989009435 @default.
- W2040347617 cites W1989529930 @default.
- W2040347617 cites W1993372138 @default.
- W2040347617 cites W1995463182 @default.
- W2040347617 cites W1996182463 @default.
- W2040347617 cites W1996411192 @default.
- W2040347617 cites W1996593652 @default.
- W2040347617 cites W1999460433 @default.
- W2040347617 cites W1999811596 @default.
- W2040347617 cites W2001311725 @default.
- W2040347617 cites W2003233519 @default.
- W2040347617 cites W2006663149 @default.
- W2040347617 cites W2009234042 @default.
- W2040347617 cites W2010344352 @default.
- W2040347617 cites W2013919311 @default.
- W2040347617 cites W2014810559 @default.
- W2040347617 cites W2015234270 @default.
- W2040347617 cites W2016516727 @default.
- W2040347617 cites W2024060072 @default.
- W2040347617 cites W2026669029 @default.
- W2040347617 cites W2026986365 @default.
- W2040347617 cites W2029003803 @default.
- W2040347617 cites W2029938137 @default.
- W2040347617 cites W2036231986 @default.
- W2040347617 cites W2037846869 @default.
- W2040347617 cites W2038729526 @default.
- W2040347617 cites W2038929318 @default.
- W2040347617 cites W2038972314 @default.
- W2040347617 cites W2048837903 @default.
- W2040347617 cites W2050507614 @default.
- W2040347617 cites W2055862436 @default.
- W2040347617 cites W2058772007 @default.
- W2040347617 cites W2061958599 @default.
- W2040347617 cites W2063164486 @default.
- W2040347617 cites W2064303674 @default.
- W2040347617 cites W2065610892 @default.
- W2040347617 cites W2072712013 @default.
- W2040347617 cites W2072864417 @default.
- W2040347617 cites W2073136162 @default.
- W2040347617 cites W2073688840 @default.
- W2040347617 cites W2078629695 @default.
- W2040347617 cites W2083313989 @default.
- W2040347617 cites W2085561902 @default.
- W2040347617 cites W2089304707 @default.
- W2040347617 cites W2089669286 @default.
- W2040347617 cites W2089923614 @default.
- W2040347617 cites W2091956372 @default.
- W2040347617 cites W2106423890 @default.
- W2040347617 cites W2111104483 @default.
- W2040347617 cites W2123998092 @default.
- W2040347617 cites W2136539233 @default.
- W2040347617 cites W2140925885 @default.
- W2040347617 cites W2152012675 @default.
- W2040347617 cites W2152752812 @default.
- W2040347617 cites W2159240849 @default.
- W2040347617 cites W2320165883 @default.
- W2040347617 cites W2330066175 @default.
- W2040347617 cites W2626393886 @default.
- W2040347617 doi "https://doi.org/10.1016/j.micromeso.2012.11.033" @default.
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