Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040352008> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2040352008 endingPage "583" @default.
- W2040352008 startingPage "577" @default.
- W2040352008 abstract "Metabotropic glutamate receptors (mGluRs) can modulate synaptic transmission, and there is evidence that phosphoinositide (PI)-linked mGluRs may be involved in sensory-dependent plasticity during the development of cat visual cortex. Consequently, we asked the questions: Where are the PI-linked mGluRs (mGluR1alpha and mGluR5) in the visual cortex? Does the quantity and distribution of these receptors change in the cat visual cortex during postnatal development, and are these features sensory-dependent? We found that the quantity of mGluR1alpha decreases with age, whereas the laminar distribution of mGluR1alpha remains the same. Quantity of mGluR5 also decreases, but the laminar distribution of mGluR5 changes during development. The pattern and timing of the mGluR5 change in distribution follow the development of geniculocortical afferents. Immunostaining indicates that reduction of receptor occurs mainly in layers V-VI for mGluR1alpha and outside layer IV for mGluR5. Dark-rearing postpones the laminar change of mGluR5 and produces an increased level of mGluR5 between postnatal 1.5-6 weeks of age but has no significant effect on the mGluR1alpha distribution or the mGluR1alpha quantity. These results suggest that mGluR1alpha and mGluR5 are involved in different aspects of cortical development. The mGluR5 is more likely to be involved in sensory-dependent events than mGluR1alpha. The lack of developmental correlation between mGluR quantities and the critical period for ocular dominance plasticity also suggests that other factors besides mGluR quantities are important for ocular dominance plasticity." @default.
- W2040352008 created "2016-06-24" @default.
- W2040352008 creator A5002098574 @default.
- W2040352008 creator A5027656877 @default.
- W2040352008 creator A5058543381 @default.
- W2040352008 creator A5061359578 @default.
- W2040352008 date "1997-12-29" @default.
- W2040352008 modified "2023-10-18" @default.
- W2040352008 title "Developmental and sensory-dependent changes of phosphoinositide-linked metabotropic glutamate receptors" @default.
- W2040352008 cites W1969357031 @default.
- W2040352008 cites W1977850041 @default.
- W2040352008 cites W1983956991 @default.
- W2040352008 cites W1986139782 @default.
- W2040352008 cites W1994310760 @default.
- W2040352008 cites W1996805443 @default.
- W2040352008 cites W2001747644 @default.
- W2040352008 cites W2003058141 @default.
- W2040352008 cites W2004005578 @default.
- W2040352008 cites W2005583444 @default.
- W2040352008 cites W2010381566 @default.
- W2040352008 cites W2017615879 @default.
- W2040352008 cites W2033188783 @default.
- W2040352008 cites W2035245157 @default.
- W2040352008 cites W2038826547 @default.
- W2040352008 cites W2050027515 @default.
- W2040352008 cites W2050419480 @default.
- W2040352008 cites W2056031247 @default.
- W2040352008 cites W2068393215 @default.
- W2040352008 cites W2072813256 @default.
- W2040352008 cites W2072818925 @default.
- W2040352008 cites W2083978441 @default.
- W2040352008 cites W2088559138 @default.
- W2040352008 cites W2088912528 @default.
- W2040352008 cites W2092217266 @default.
- W2040352008 cites W2098150710 @default.
- W2040352008 cites W2102088561 @default.
- W2040352008 cites W2104220712 @default.
- W2040352008 cites W2130077267 @default.
- W2040352008 cites W2138773372 @default.
- W2040352008 cites W4300258638 @default.
- W2040352008 cites W46314225 @default.
- W2040352008 doi "https://doi.org/10.1002/(sici)1096-9861(19971229)389:4<577::aid-cne3>3.0.co;2-y" @default.
- W2040352008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9421140" @default.
- W2040352008 hasPublicationYear "1997" @default.
- W2040352008 type Work @default.
- W2040352008 sameAs 2040352008 @default.
- W2040352008 citedByCount "28" @default.
- W2040352008 countsByYear W20403520082018 @default.
- W2040352008 crossrefType "journal-article" @default.
- W2040352008 hasAuthorship W2040352008A5002098574 @default.
- W2040352008 hasAuthorship W2040352008A5027656877 @default.
- W2040352008 hasAuthorship W2040352008A5058543381 @default.
- W2040352008 hasAuthorship W2040352008A5061359578 @default.
- W2040352008 hasConcept C169760540 @default.
- W2040352008 hasConcept C170493617 @default.
- W2040352008 hasConcept C2779345533 @default.
- W2040352008 hasConcept C41653306 @default.
- W2040352008 hasConcept C49051014 @default.
- W2040352008 hasConcept C55493867 @default.
- W2040352008 hasConcept C6084040 @default.
- W2040352008 hasConcept C61174792 @default.
- W2040352008 hasConcept C86803240 @default.
- W2040352008 hasConcept C94487597 @default.
- W2040352008 hasConceptScore W2040352008C169760540 @default.
- W2040352008 hasConceptScore W2040352008C170493617 @default.
- W2040352008 hasConceptScore W2040352008C2779345533 @default.
- W2040352008 hasConceptScore W2040352008C41653306 @default.
- W2040352008 hasConceptScore W2040352008C49051014 @default.
- W2040352008 hasConceptScore W2040352008C55493867 @default.
- W2040352008 hasConceptScore W2040352008C6084040 @default.
- W2040352008 hasConceptScore W2040352008C61174792 @default.
- W2040352008 hasConceptScore W2040352008C86803240 @default.
- W2040352008 hasConceptScore W2040352008C94487597 @default.
- W2040352008 hasIssue "4" @default.
- W2040352008 hasLocation W20403520081 @default.
- W2040352008 hasLocation W20403520082 @default.
- W2040352008 hasOpenAccess W2040352008 @default.
- W2040352008 hasPrimaryLocation W20403520081 @default.
- W2040352008 hasRelatedWork W1976151591 @default.
- W2040352008 hasRelatedWork W1989867524 @default.
- W2040352008 hasRelatedWork W2074660916 @default.
- W2040352008 hasRelatedWork W2138327177 @default.
- W2040352008 hasRelatedWork W2424328599 @default.
- W2040352008 hasRelatedWork W2889054662 @default.
- W2040352008 hasRelatedWork W3165559032 @default.
- W2040352008 hasRelatedWork W3195491161 @default.
- W2040352008 hasRelatedWork W4244410293 @default.
- W2040352008 hasRelatedWork W2188245770 @default.
- W2040352008 hasVolume "389" @default.
- W2040352008 isParatext "false" @default.
- W2040352008 isRetracted "false" @default.
- W2040352008 magId "2040352008" @default.
- W2040352008 workType "article" @default.