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- W2040363594 abstract "In order to demonstrate direct cortico-motoneuronal synaptic contacts in the cervical spinal cord of the rat and to determine at which postnatal age these contacts are established, an electron microscopic study using double labelling was performed. Corticospinal axons were anterogradely labelled after horseradish peroxidase (HRP)-gel implantation into the cerebral motor cortex and motoneurons were retrogradely labelled after cholera toxin subunit B conjugated to HRP (CTB-HRP) injections into the distal forelimb flexor muscle. With the histochemical procedures used, both tracers yield similar needle-like crystalline deposits. Labelled axons, however, can be well differentiated from labelled motoneuronal dendrites and somata on morphological grounds. In adult rats, direct cortico-motoneuronal contacts were encountered. Experiments in developing postnatal rats demonstrated that these synapses are first present on postnatal day 7." @default.
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- W2040363594 title "Direct cortico-motoneuronal synaptic contacts are present in the adult rat cervical spinal cord and are first established at postnatal day 7" @default.
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- W2040363594 doi "https://doi.org/10.1016/0304-3940(96)12396-x" @default.
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