FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040366758> ?p ?o ?g. }

• W2040366758 endingPage "545" @default.
• W2040366758 startingPage "537" @default.
• W2040366758 abstract "Impact loading causes cartilage damage and cell death. Pre-loading prior to impact loading may protect cartilage and chondrocytes. However, there is no systematic evidence and understanding of the effects of pre-load strategies on cartilage damage and chondrocyte death. This study aimed at determining the effects of the pre-load history on impact-induced chondrocyte death in an intact joint.Patellofemoral joints from 42 rabbits were loaded by controlled quadriceps muscle contractions and an external impacter. Two extreme muscular loading conditions were used: (i) a short-duration, high intensity, static muscle contraction, and (ii) a long-duration, low-intensity, cyclic muscle loading protocol. A 5-Joule centrally-oriented, gravity-accelerated impact load was applied to the joints. Chondrocyte viability was quantified following the muscular loading protocols, following application of the isolated impact loads, and following application of the impact loads that were preceded by the muscular pre-loads. Joint contact pressures were measured for all loading conditions by a pressure-sensitive film.Comparing to cartilage injured by impact loading alone, cartilage pre-loaded by static, maximal intensity, short-term muscle loads had lower cell death, while cartilage pre-loaded by repetitive, low-intensity, long-term muscular loads has higher cell death. The locations of peak joint contact pressures were not strongly correlated with the locations of greatest cell death occurrence.Static, high intensity, short muscular pre-load protected cells from impact injury, whereas repetitive, low intensity, prolonged muscular pre-loading to the point of muscular fatigue left the chondrocytes vulnerable to injury. However, cell death seems to be unrelated to the peak joint pressures." @default.
• W2040366758 created "2016-06-24" @default.
• W2040366758 creator A5013903559 @default.
• W2040366758 creator A5055496476 @default.
• W2040366758 creator A5069322953 @default.
• W2040366758 date "2015-07-01" @default.
• W2040366758 modified "2023-09-26" @default.
• W2040366758 title "Cartilage and chondrocyte response to extreme muscular loading and impact loading: Can in vivo pre-load decrease impact-induced cell death?" @default.
• W2040366758 cites W1487036716 @default.
• W2040366758 cites W1533739166 @default.
• W2040366758 cites W1595739217 @default.
• W2040366758 cites W1964274570 @default.
• W2040366758 cites W1964733918 @default.
• W2040366758 cites W1969693271 @default.
• W2040366758 cites W1973557647 @default.
• W2040366758 cites W1976971109 @default.
• W2040366758 cites W1977679020 @default.
• W2040366758 cites W1990074161 @default.
• W2040366758 cites W1990566466 @default.
• W2040366758 cites W1996841581 @default.
• W2040366758 cites W2000967069 @default.
• W2040366758 cites W2001254210 @default.
• W2040366758 cites W2001552074 @default.
• W2040366758 cites W2023098824 @default.
• W2040366758 cites W2024504609 @default.
• W2040366758 cites W2024960977 @default.
• W2040366758 cites W2025081598 @default.
• W2040366758 cites W2029466843 @default.
• W2040366758 cites W2029712661 @default.
• W2040366758 cites W2031592383 @default.
• W2040366758 cites W2032163159 @default.
• W2040366758 cites W2035921958 @default.
• W2040366758 cites W2039050516 @default.
• W2040366758 cites W2043245049 @default.
• W2040366758 cites W2043696490 @default.
• W2040366758 cites W2044210168 @default.
• W2040366758 cites W2047636197 @default.
• W2040366758 cites W2048908624 @default.
• W2040366758 cites W2050177842 @default.
• W2040366758 cites W2054808502 @default.
• W2040366758 cites W2057657657 @default.
• W2040366758 cites W2062753577 @default.
• W2040366758 cites W2064416373 @default.
• W2040366758 cites W2065499250 @default.
• W2040366758 cites W2065989893 @default.
• W2040366758 cites W2066657539 @default.
• W2040366758 cites W2067244632 @default.
• W2040366758 cites W2073411267 @default.
• W2040366758 cites W2078899826 @default.
• W2040366758 cites W2086382719 @default.
• W2040366758 cites W2095168835 @default.
• W2040366758 cites W2101108021 @default.
• W2040366758 cites W2104754660 @default.
• W2040366758 cites W2116010693 @default.
• W2040366758 cites W2134617611 @default.
• W2040366758 cites W2135850782 @default.
• W2040366758 cites W2148881810 @default.
• W2040366758 cites W2150373299 @default.
• W2040366758 cites W2153472991 @default.
• W2040366758 cites W2163426109 @default.
• W2040366758 cites W2167037356 @default.
• W2040366758 cites W2167245751 @default.
• W2040366758 cites W4241641521 @default.
• W2040366758 cites W4247214431 @default.
• W2040366758 doi "https://doi.org/10.1016/j.clinbiomech.2015.04.009" @default.
• W2040366758 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25957254" @default.
• W2040366758 hasPublicationYear "2015" @default.
• W2040366758 type Work @default.
• W2040366758 sameAs 2040366758 @default.
• W2040366758 citedByCount "9" @default.
• W2040366758 countsByYear W20403667582016 @default.
• W2040366758 countsByYear W20403667582018 @default.
• W2040366758 countsByYear W20403667582020 @default.
• W2040366758 countsByYear W20403667582021 @default.
• W2040366758 countsByYear W20403667582023 @default.
• W2040366758 crossrefType "journal-article" @default.
• W2040366758 hasAuthorship W2040366758A5013903559 @default.
• W2040366758 hasAuthorship W2040366758A5055496476 @default.
• W2040366758 hasAuthorship W2040366758A5069322953 @default.
• W2040366758 hasBestOaLocation W20403667582 @default.
• W2040366758 hasConcept C105702510 @default.
• W2040366758 hasConcept C121332964 @default.
• W2040366758 hasConcept C136229726 @default.
• W2040366758 hasConcept C192562407 @default.
• W2040366758 hasConcept C2780550940 @default.
• W2040366758 hasConcept C2781403057 @default.
• W2040366758 hasConcept C62520636 @default.
• W2040366758 hasConcept C71924100 @default.
• W2040366758 hasConcept C93038891 @default.
• W2040366758 hasConceptScore W2040366758C105702510 @default.
• W2040366758 hasConceptScore W2040366758C121332964 @default.
• W2040366758 hasConceptScore W2040366758C136229726 @default.
• W2040366758 hasConceptScore W2040366758C192562407 @default.
• W2040366758 hasConceptScore W2040366758C2780550940 @default.
• W2040366758 hasConceptScore W2040366758C2781403057 @default.
• W2040366758 hasConceptScore W2040366758C62520636 @default.
• W2040366758 hasConceptScore W2040366758C71924100 @default.
• W2040366758 hasConceptScore W2040366758C93038891 @default.

• next