FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040372855> ?p ?o ?g. }

• W2040372855 endingPage "398" @default.
• W2040372855 startingPage "393" @default.
• W2040372855 abstract "Chronic kidney disease (CKD) is common and is associated with increased mortality in heart failure (HF). However, it is unknown whether the effect of CKD on mortality varies by left ventricular ejection fraction (LVEF). We evaluated the effect of CKD on mortality in patients with systolic (LVEF <or=45%) and diastolic (LVEF >45%) HF. Of the 7,788 patients in the Digitalis Investigation Group trial, 3,527 (45%) had CKD (estimated glomerular filtration rate <60 ml/min/1.73 m2). We calculated the propensity score for CKD for each patient, using a multivariate logistic regression model (c statistic 0.76, postmatch absolute standardized differences <5% for all 32 co-variates). We matched 2,399 pairs of patients with and without CKD with similar propensity scores. There were 757 (rate 1,049/10,000 person-years) and 882 (rate 1,282/10,000 person-years) deaths, respectively, in patients without and with CKD (hazard ratio 1.22, 95% confidence interval 1.09 to 1.36, p <0.0001). CKD-associated mortality was higher in those with diastolic HF (371 extra deaths/10,000 person-years, hazard ratio 1.71, 95% confidence interval 1.21 to 2.41, p = 0.002) than in systolic HF (214 extra deaths/10,000 person-years, hazard ratio 1.19, 95% confidence interval 1.07 to 1.32, p = 0.001), which was significant (adjusted p for interaction = 0.034). A graded association was found between CKD-related deaths and LVEF. The hazard ratios for CKD-associated mortality for the LVEF subgroups of <35%, 35% to 55%, and >55% were 1.15 (95% confidence interval 1.02 to 1.29), 1.35 (95% confidence interval 1.11 to 1.64), and 2.33 (95% confidence interval 1.34 to 4.06). In conclusion, CKD-associated mortality was higher in those with diastolic than systolic HF. Patients with diastolic HF should be evaluated for CKD, and the role of inhibitors of the renin-angiotensin system in these patients needs to be investigated." @default.
• W2040372855 created "2016-06-24" @default.
• W2040372855 creator A5011794653 @default.
• W2040372855 creator A5012514694 @default.
• W2040372855 creator A5016506193 @default.
• W2040372855 creator A5021094428 @default.
• W2040372855 creator A5030873899 @default.
• W2040372855 creator A5047833899 @default.
• W2040372855 creator A5056020540 @default.
• W2040372855 creator A5071585977 @default.
• W2040372855 creator A5079841033 @default.
• W2040372855 date "2007-02-01" @default.
• W2040372855 modified "2023-10-02" @default.
• W2040372855 title "Chronic Kidney Disease Associated Mortality in Diastolic Versus Systolic Heart Failure: A Propensity Matched Study††The Digitalis Investigation Group study was conducted and supported by the National Heart, Lung, and Blood Institute in collaboration with the Digitalis Investigation Group Investigators. This manuscript was prepared using a limited access data set obtained by the National Heart, Lung, and Blood Institute and does not necessarily reflect the opinions or views of the Digitalis …" @default.
• W2040372855 cites W1966337012 @default.
• W2040372855 cites W1983233922 @default.
• W2040372855 cites W2004733118 @default.
• W2040372855 cites W2007909440 @default.
• W2040372855 cites W2013832234 @default.
• W2040372855 cites W2055864845 @default.
• W2040372855 cites W2060860307 @default.
• W2040372855 cites W2069770709 @default.
• W2040372855 cites W2092938685 @default.
• W2040372855 cites W2098364806 @default.
• W2040372855 cites W2132517877 @default.
• W2040372855 cites W2133084764 @default.
• W2040372855 cites W2135810490 @default.
• W2040372855 cites W2148173212 @default.
• W2040372855 cites W2155559652 @default.
• W2040372855 cites W2158987804 @default.
• W2040372855 cites W2340731691 @default.
• W2040372855 cites W2597503617 @default.
• W2040372855 cites W2607031541 @default.
• W2040372855 cites W2945068164 @default.
• W2040372855 cites W4239728164 @default.
• W2040372855 cites W4253805124 @default.
• W2040372855 doi "https://doi.org/10.1016/j.amjcard.2006.08.042" @default.
• W2040372855 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2708087" @default.
• W2040372855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17261405" @default.
• W2040372855 hasPublicationYear "2007" @default.
• W2040372855 type Work @default.
• W2040372855 sameAs 2040372855 @default.
• W2040372855 citedByCount "222" @default.
• W2040372855 countsByYear W20403728552012 @default.
• W2040372855 countsByYear W20403728552013 @default.
• W2040372855 countsByYear W20403728552014 @default.
• W2040372855 countsByYear W20403728552015 @default.
• W2040372855 countsByYear W20403728552016 @default.
• W2040372855 countsByYear W20403728552017 @default.
• W2040372855 countsByYear W20403728552018 @default.
• W2040372855 countsByYear W20403728552019 @default.
• W2040372855 countsByYear W20403728552020 @default.
• W2040372855 countsByYear W20403728552021 @default.
• W2040372855 countsByYear W20403728552022 @default.
• W2040372855 countsByYear W20403728552023 @default.
• W2040372855 crossrefType "journal-article" @default.
• W2040372855 hasAuthorship W2040372855A5011794653 @default.
• W2040372855 hasAuthorship W2040372855A5012514694 @default.
• W2040372855 hasAuthorship W2040372855A5016506193 @default.
• W2040372855 hasAuthorship W2040372855A5021094428 @default.
• W2040372855 hasAuthorship W2040372855A5030873899 @default.
• W2040372855 hasAuthorship W2040372855A5047833899 @default.
• W2040372855 hasAuthorship W2040372855A5056020540 @default.
• W2040372855 hasAuthorship W2040372855A5071585977 @default.
• W2040372855 hasAuthorship W2040372855A5079841033 @default.
• W2040372855 hasBestOaLocation W20403728552 @default.
• W2040372855 hasConcept C126322002 @default.
• W2040372855 hasConcept C159641895 @default.
• W2040372855 hasConcept C164705383 @default.
• W2040372855 hasConcept C2778198053 @default.
• W2040372855 hasConcept C2778653478 @default.
• W2040372855 hasConcept C2779781611 @default.
• W2040372855 hasConcept C44249647 @default.
• W2040372855 hasConcept C57900726 @default.
• W2040372855 hasConcept C71924100 @default.
• W2040372855 hasConcept C78085059 @default.
• W2040372855 hasConcept C84393581 @default.
• W2040372855 hasConceptScore W2040372855C126322002 @default.
• W2040372855 hasConceptScore W2040372855C159641895 @default.
• W2040372855 hasConceptScore W2040372855C164705383 @default.
• W2040372855 hasConceptScore W2040372855C2778198053 @default.
• W2040372855 hasConceptScore W2040372855C2778653478 @default.
• W2040372855 hasConceptScore W2040372855C2779781611 @default.
• W2040372855 hasConceptScore W2040372855C44249647 @default.
• W2040372855 hasConceptScore W2040372855C57900726 @default.
• W2040372855 hasConceptScore W2040372855C71924100 @default.
• W2040372855 hasConceptScore W2040372855C78085059 @default.
• W2040372855 hasConceptScore W2040372855C84393581 @default.
• W2040372855 hasIssue "3" @default.
• W2040372855 hasLocation W20403728551 @default.
• W2040372855 hasLocation W20403728552 @default.
• W2040372855 hasLocation W20403728553 @default.
• W2040372855 hasLocation W20403728554 @default.
• W2040372855 hasOpenAccess W2040372855 @default.
• W2040372855 hasPrimaryLocation W20403728551 @default.
• W2040372855 hasRelatedWork W1830880092 @default.
• W2040372855 hasRelatedWork W1949634191 @default.
• W2040372855 hasRelatedWork W1964205598 @default.

• next