FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040376048> ?p ?o ?g. }

• W2040376048 endingPage "136" @default.
• W2040376048 startingPage "129" @default.
• W2040376048 abstract "Brevibacterium linens can grow in media of relatively high osmotic strength (up to 3 m-NaCl). Optimal growth in minimal medium occurred with either added NaCl (0·5–1 m) or other osmolytes developing an equivalent osmotic pressure. Above 1 m-NaCl the growth rate slowed, but was enhanced by adding the osmoprotectant glycine betaine or its precursor choline (1 mm) to the media. Neither soluble carbohydrates nor ninhydrin-reacting compounds accumulated during osmotic treatment. However, a Dragendorff-positive compound, together with K+ ions, accumulated (7-fold) as a consequence of elevating the medium osmolality. Spectral characteristics of the purified compound were similar to those of synthesized 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid (ectoine). In the absence of exogenously supplied osmoprotectants, a strict dependence between the intracellular ectoine content and the external salt concentration (up to 1 m-NaCl) was observed. From 1 to 2 m-NaCl, the ectoine content decreased, and this signalled decreased self-osmoprotection by this bacterium. Interestingly, at these salt concentrations, exogenous glycine betaine led to the greatest beneficial effect. Glycine betaine or choline added to the medium was actively taken up by the cells in an osmolality-dependent manner, and the resulting betaine accumulation caused a sharp decrease in intracellular ectoine content. Radiolabelling of ectoine occurred only when l-[U-14C]glutamate was used as a precursor; de novo synthesis was dependent on the external osmolality and was strongly inhibited by exogenously supplied glycine betaine. These results imply that ectoine may play a major role in counteracting the effects of osmotic stress in media of osmotic pressure equivalent to ≤ 1 m-NaCl." @default.
• W2040376048 created "2016-06-24" @default.
• W2040376048 creator A5016833326 @default.
• W2040376048 creator A5038947968 @default.
• W2040376048 creator A5042282512 @default.
• W2040376048 creator A5048336529 @default.
• W2040376048 creator A5072774621 @default.
• W2040376048 creator A5085709934 @default.
• W2040376048 date "1993-01-01" @default.
• W2040376048 modified "2023-10-14" @default.
• W2040376048 title "Ectoine accumulation and osmotic regulation in Brevibacterium linens" @default.
• W2040376048 cites W1493971942 @default.
• W2040376048 cites W1518290678 @default.
• W2040376048 cites W1529084957 @default.
• W2040376048 cites W1530026900 @default.
• W2040376048 cites W1546665090 @default.
• W2040376048 cites W1546783991 @default.
• W2040376048 cites W1577458838 @default.
• W2040376048 cites W1580982499 @default.
• W2040376048 cites W1597626888 @default.
• W2040376048 cites W1821279949 @default.
• W2040376048 cites W1918140755 @default.
• W2040376048 cites W1992949792 @default.
• W2040376048 cites W1995203966 @default.
• W2040376048 cites W2002807853 @default.
• W2040376048 cites W2039442152 @default.
• W2040376048 cites W2042998656 @default.
• W2040376048 cites W2057470797 @default.
• W2040376048 cites W2087825189 @default.
• W2040376048 cites W2092787609 @default.
• W2040376048 cites W2095960096 @default.
• W2040376048 cites W2125042590 @default.
• W2040376048 cites W2125882807 @default.
• W2040376048 cites W2126040811 @default.
• W2040376048 cites W2137180677 @default.
• W2040376048 cites W2137562565 @default.
• W2040376048 cites W2142105619 @default.
• W2040376048 cites W2143019272 @default.
• W2040376048 cites W2146753964 @default.
• W2040376048 cites W2151221165 @default.
• W2040376048 cites W2153662465 @default.
• W2040376048 cites W2157063927 @default.
• W2040376048 doi "https://doi.org/10.1099/00221287-139-1-129" @default.
• W2040376048 hasPublicationYear "1993" @default.
• W2040376048 type Work @default.
• W2040376048 sameAs 2040376048 @default.
• W2040376048 citedByCount "86" @default.
• W2040376048 countsByYear W20403760482012 @default.
• W2040376048 countsByYear W20403760482013 @default.
• W2040376048 countsByYear W20403760482014 @default.
• W2040376048 countsByYear W20403760482015 @default.
• W2040376048 countsByYear W20403760482016 @default.
• W2040376048 countsByYear W20403760482018 @default.
• W2040376048 countsByYear W20403760482019 @default.
• W2040376048 countsByYear W20403760482021 @default.
• W2040376048 countsByYear W20403760482023 @default.
• W2040376048 crossrefType "journal-article" @default.
• W2040376048 hasAuthorship W2040376048A5016833326 @default.
• W2040376048 hasAuthorship W2040376048A5038947968 @default.
• W2040376048 hasAuthorship W2040376048A5042282512 @default.
• W2040376048 hasAuthorship W2040376048A5048336529 @default.
• W2040376048 hasAuthorship W2040376048A5072774621 @default.
• W2040376048 hasAuthorship W2040376048A5085709934 @default.
• W2040376048 hasBestOaLocation W20403760481 @default.
• W2040376048 hasConcept C127160389 @default.
• W2040376048 hasConcept C129513315 @default.
• W2040376048 hasConcept C129900496 @default.
• W2040376048 hasConcept C175605896 @default.
• W2040376048 hasConcept C185592680 @default.
• W2040376048 hasConcept C18903297 @default.
• W2040376048 hasConcept C26448091 @default.
• W2040376048 hasConcept C2777248517 @default.
• W2040376048 hasConcept C2777756961 @default.
• W2040376048 hasConcept C2778386651 @default.
• W2040376048 hasConcept C2779815552 @default.
• W2040376048 hasConcept C2780919596 @default.
• W2040376048 hasConcept C2780929338 @default.
• W2040376048 hasConcept C515207424 @default.
• W2040376048 hasConcept C523546767 @default.
• W2040376048 hasConcept C54355233 @default.
• W2040376048 hasConcept C55493867 @default.
• W2040376048 hasConcept C58415070 @default.
• W2040376048 hasConcept C86803240 @default.
• W2040376048 hasConcept C9603476 @default.
• W2040376048 hasConceptScore W2040376048C127160389 @default.
• W2040376048 hasConceptScore W2040376048C129513315 @default.
• W2040376048 hasConceptScore W2040376048C129900496 @default.
• W2040376048 hasConceptScore W2040376048C175605896 @default.
• W2040376048 hasConceptScore W2040376048C185592680 @default.
• W2040376048 hasConceptScore W2040376048C18903297 @default.
• W2040376048 hasConceptScore W2040376048C26448091 @default.
• W2040376048 hasConceptScore W2040376048C2777248517 @default.
• W2040376048 hasConceptScore W2040376048C2777756961 @default.
• W2040376048 hasConceptScore W2040376048C2778386651 @default.
• W2040376048 hasConceptScore W2040376048C2779815552 @default.
• W2040376048 hasConceptScore W2040376048C2780919596 @default.
• W2040376048 hasConceptScore W2040376048C2780929338 @default.
• W2040376048 hasConceptScore W2040376048C515207424 @default.

• next