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- W2040377593 abstract "To assess the prevalence and incidence of human T-cell lymphotropic virus type I (HTLV-I), 4,234 pregnant women of different ethnic origins were tested before each delivery between 1991 and 1997 in a high HTLV-I endemic area of French Guiana. HTLV-I was significantly more prevalent among ethnic groups of African descent as the Noir-Marrons (4.8%, 95% confidence interval [CI]: 4.0–5.6) and Haitians (5%, 95% CI 1.6–8.4). An age dependence of HTLV-I seroprevalence was observed. The mean age of Noir-Marron HTLV-I seronegative women was lower than for HTLV-I seropositive women (24.7 vs. 28.6, p < 0.001). A decline in HTLV-I seroprevalence was observed, particularly in the Noir-Marron younger than 21 years old (p = 0.04). For five HTLV-I seroconversions observed, the incidence per 100 women-years in the Noir-Marron group was 0.19 (95% CI 0.02–0.35) for all women, 0.32 in those 25 years old or younger (95% CI 0–0.64), and 0.07 in those older than 25 years (95% CI 0–0.2). This observation was inconsistent with HTLV-I seroprevalence observed for those 25 years old or younger (2.8%) and those older than 25 (8.3%). These data demonstrate, for the first time outside Japan, a birth cohort effect for HTLV-I in a highly endemic ethnic group. Int. J. Cancer 87:534–538, 2000. © 2000 Wiley-Liss, Inc." @default.
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- W2040377593 date "2000-01-01" @default.
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- W2040377593 title "Decrease of human T-cell lymphotropic virus type I prevalence and low incidence among pregnant women from a high endemic ethnic group in French Guiana" @default.
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- W2040377593 doi "https://doi.org/10.1002/1097-0215(20000815)87:4<534::aid-ijc12>3.0.co;2-m" @default.
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