Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040381793> ?p ?o ?g. }
- W2040381793 endingPage "2555" @default.
- W2040381793 startingPage "2545" @default.
- W2040381793 abstract "The CCAAT/enhancer-binding protein (C/EBP) family of transcription factors plays an important role in controlling cell proliferation and differentiation. C/EBPα is a particularly potent regulator of cell-cycle exit and is induced in terminally differentiating adipocytes and myeloid cells, where it also activates differentiation-specific genes. The growth-inhibiting activity of C/EBPα suppresses tumorigenesis in myeloid cells and possibly other tissues. In addition, recent work has identified C/EBPα as a component of the p53-regulated growth arrest response elicited by DNA damage in epidermal keratinocytes. Several studies have explored the mechanism by which C/EBPα blocks cell-cycle progression at the G1-S boundary, and several models have been proposed but no universally accepted mechanism has emerged. Controversial issues include whether C/EBPα acts through an `off-DNA' mechanism to inhibit cyclin-dependent kinases, and whether and how it functions with the RB-E2F system to repress transcription of S-phase genes. Other C/EBP-family members have also been implicated in positive and negative control of cell proliferation, and the mechanisms underlying their growth-regulatory activities are beginning to be elucidated." @default.
- W2040381793 created "2016-06-24" @default.
- W2040381793 creator A5018475996 @default.
- W2040381793 date "2005-06-15" @default.
- W2040381793 modified "2023-10-17" @default.
- W2040381793 title "Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors" @default.
- W2040381793 cites W1489323849 @default.
- W2040381793 cites W1526419517 @default.
- W2040381793 cites W1558208327 @default.
- W2040381793 cites W161652132 @default.
- W2040381793 cites W1819665821 @default.
- W2040381793 cites W1852811226 @default.
- W2040381793 cites W1919219011 @default.
- W2040381793 cites W1963486017 @default.
- W2040381793 cites W1964842789 @default.
- W2040381793 cites W1965349495 @default.
- W2040381793 cites W1971533139 @default.
- W2040381793 cites W1981860701 @default.
- W2040381793 cites W1982017174 @default.
- W2040381793 cites W1983585255 @default.
- W2040381793 cites W1987598864 @default.
- W2040381793 cites W1988059168 @default.
- W2040381793 cites W1989481014 @default.
- W2040381793 cites W1993600035 @default.
- W2040381793 cites W1995322263 @default.
- W2040381793 cites W1997087173 @default.
- W2040381793 cites W1998492363 @default.
- W2040381793 cites W2001004678 @default.
- W2040381793 cites W2003184529 @default.
- W2040381793 cites W2007263769 @default.
- W2040381793 cites W2007443158 @default.
- W2040381793 cites W2009046213 @default.
- W2040381793 cites W2014620140 @default.
- W2040381793 cites W2015198577 @default.
- W2040381793 cites W2018307328 @default.
- W2040381793 cites W2019088616 @default.
- W2040381793 cites W2019540980 @default.
- W2040381793 cites W2020649739 @default.
- W2040381793 cites W2022815760 @default.
- W2040381793 cites W2023544072 @default.
- W2040381793 cites W2025505666 @default.
- W2040381793 cites W2029824360 @default.
- W2040381793 cites W2037742127 @default.
- W2040381793 cites W2037805235 @default.
- W2040381793 cites W2038912397 @default.
- W2040381793 cites W2040937550 @default.
- W2040381793 cites W2047842452 @default.
- W2040381793 cites W2049629344 @default.
- W2040381793 cites W2050249118 @default.
- W2040381793 cites W2051787132 @default.
- W2040381793 cites W2054737276 @default.
- W2040381793 cites W2055627135 @default.
- W2040381793 cites W2060865120 @default.
- W2040381793 cites W2069548932 @default.
- W2040381793 cites W2074733595 @default.
- W2040381793 cites W2078853769 @default.
- W2040381793 cites W2082099893 @default.
- W2040381793 cites W2083483484 @default.
- W2040381793 cites W2085917809 @default.
- W2040381793 cites W2086524102 @default.
- W2040381793 cites W2087404852 @default.
- W2040381793 cites W2090376385 @default.
- W2040381793 cites W2098974513 @default.
- W2040381793 cites W2100088478 @default.
- W2040381793 cites W2104775085 @default.
- W2040381793 cites W2108342665 @default.
- W2040381793 cites W2114538465 @default.
- W2040381793 cites W2114994407 @default.
- W2040381793 cites W2115114534 @default.
- W2040381793 cites W2115413477 @default.
- W2040381793 cites W2123180955 @default.
- W2040381793 cites W2124753274 @default.
- W2040381793 cites W2127621383 @default.
- W2040381793 cites W2127632559 @default.
- W2040381793 cites W2130235275 @default.
- W2040381793 cites W2133162368 @default.
- W2040381793 cites W2135374851 @default.
- W2040381793 cites W2135855901 @default.
- W2040381793 cites W2137105120 @default.
- W2040381793 cites W2141096844 @default.
- W2040381793 cites W2147639446 @default.
- W2040381793 cites W2150777358 @default.
- W2040381793 cites W2153722393 @default.
- W2040381793 cites W2155549511 @default.
- W2040381793 cites W2162564085 @default.
- W2040381793 cites W2163399650 @default.
- W2040381793 cites W2164599211 @default.
- W2040381793 cites W2269438046 @default.
- W2040381793 cites W2321987491 @default.
- W2040381793 cites W2404828585 @default.
- W2040381793 cites W321874077 @default.
- W2040381793 cites W4294988796 @default.
- W2040381793 doi "https://doi.org/10.1242/jcs.02459" @default.
- W2040381793 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15944395" @default.
- W2040381793 hasPublicationYear "2005" @default.
- W2040381793 type Work @default.
- W2040381793 sameAs 2040381793 @default.
- W2040381793 citedByCount "269" @default.