FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040389318> ?p ?o ?g. }

• W2040389318 abstract "Antiphospholipid antibody syndrome (APS) is a complex autoimmune thrombotic disorder with defined clinical phenotypes. Although not all patients with elevated antiphospholipid antibody (aPLA) levels develop complications, the severity of these potential events mandates aggressive and extended lifelong anti-thrombotic therapy. One hundred twenty-nine patients (57 patients with APS and venous thromboembolism [VTE], 32 patients with VTE without aPLA, 32 patients with aPLA only, and 8 healthy patients) were enrolled. RNA from peripheral-blood collection was used for DNA microarray analysis. Patterns of gene expression that characterize APS as well as thrombosis in the presence of aPLA were identified by hierarchical clustering and binary regression methods. Gene-expression profiles identify and predict individuals with APS from patients with VTE without aPLA. Importantly, similar methods identified expression profiles that accurately predicted those patients with aPLA at high risk for thrombotic events. All profiles were validated in independent cohorts of patients. The ability to predict APS, but more importantly, those patients at risk for venous thrombosis, represents a paradigm for a genomic approach that can be applied to other populations of patients with venous thrombosis, providing for more effective clinical management of disease, while also reflecting the possible underlying biologic processes." @default.
• W2040389318 created "2016-06-24" @default.
• W2040389318 creator A5016251947 @default.
• W2040389318 creator A5048770508 @default.
• W2040389318 creator A5052647492 @default.
• W2040389318 creator A5057494906 @default.
• W2040389318 creator A5069172766 @default.
• W2040389318 creator A5072788736 @default.
• W2040389318 date "2006-02-15" @default.
• W2040389318 modified "2023-10-10" @default.
• W2040389318 title "Gene-expression patterns predict phenotypes of immune-mediated thrombosis" @default.
• W2040389318 cites W1564416982 @default.
• W2040389318 cites W1596313173 @default.
• W2040389318 cites W1862054033 @default.
• W2040389318 cites W188384924 @default.
• W2040389318 cites W1974222492 @default.
• W2040389318 cites W1979904797 @default.
• W2040389318 cites W1985935781 @default.
• W2040389318 cites W1991721757 @default.
• W2040389318 cites W1997533866 @default.
• W2040389318 cites W2000055469 @default.
• W2040389318 cites W2003916081 @default.
• W2040389318 cites W2008249964 @default.
• W2040389318 cites W2054674683 @default.
• W2040389318 cites W2079375655 @default.
• W2040389318 cites W2080250830 @default.
• W2040389318 cites W2088071042 @default.
• W2040389318 cites W2091487852 @default.
• W2040389318 cites W2101831374 @default.
• W2040389318 cites W2108043112 @default.
• W2040389318 cites W2113891001 @default.
• W2040389318 cites W2160193995 @default.
• W2040389318 cites W2168561598 @default.
• W2040389318 cites W2199241379 @default.
• W2040389318 cites W2351825040 @default.
• W2040389318 cites W2415371444 @default.
• W2040389318 cites W2470337057 @default.
• W2040389318 cites W4213347641 @default.
• W2040389318 cites W4231434854 @default.
• W2040389318 doi "https://doi.org/10.1182/blood-2005-07-2669" @default.
• W2040389318 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1895419" @default.
• W2040389318 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16263789" @default.
• W2040389318 hasPublicationYear "2006" @default.
• W2040389318 type Work @default.
• W2040389318 sameAs 2040389318 @default.
• W2040389318 citedByCount "49" @default.
• W2040389318 countsByYear W20403893182012 @default.
• W2040389318 countsByYear W20403893182013 @default.
• W2040389318 countsByYear W20403893182014 @default.
• W2040389318 countsByYear W20403893182016 @default.
• W2040389318 countsByYear W20403893182017 @default.
• W2040389318 countsByYear W20403893182020 @default.
• W2040389318 countsByYear W20403893182021 @default.
• W2040389318 crossrefType "journal-article" @default.
• W2040389318 hasAuthorship W2040389318A5016251947 @default.
• W2040389318 hasAuthorship W2040389318A5048770508 @default.
• W2040389318 hasAuthorship W2040389318A5052647492 @default.
• W2040389318 hasAuthorship W2040389318A5057494906 @default.
• W2040389318 hasAuthorship W2040389318A5069172766 @default.
• W2040389318 hasAuthorship W2040389318A5072788736 @default.
• W2040389318 hasBestOaLocation W20403893181 @default.
• W2040389318 hasConcept C104317684 @default.
• W2040389318 hasConcept C126322002 @default.
• W2040389318 hasConcept C127716648 @default.
• W2040389318 hasConcept C203014093 @default.
• W2040389318 hasConcept C2776874634 @default.
• W2040389318 hasConcept C2780011451 @default.
• W2040389318 hasConcept C2780868729 @default.
• W2040389318 hasConcept C54355233 @default.
• W2040389318 hasConcept C60644358 @default.
• W2040389318 hasConcept C71924100 @default.
• W2040389318 hasConcept C86803240 @default.
• W2040389318 hasConceptScore W2040389318C104317684 @default.
• W2040389318 hasConceptScore W2040389318C126322002 @default.
• W2040389318 hasConceptScore W2040389318C127716648 @default.
• W2040389318 hasConceptScore W2040389318C203014093 @default.
• W2040389318 hasConceptScore W2040389318C2776874634 @default.
• W2040389318 hasConceptScore W2040389318C2780011451 @default.
• W2040389318 hasConceptScore W2040389318C2780868729 @default.
• W2040389318 hasConceptScore W2040389318C54355233 @default.
• W2040389318 hasConceptScore W2040389318C60644358 @default.
• W2040389318 hasConceptScore W2040389318C71924100 @default.
• W2040389318 hasConceptScore W2040389318C86803240 @default.
• W2040389318 hasLocation W20403893181 @default.
• W2040389318 hasLocation W20403893182 @default.
• W2040389318 hasLocation W20403893183 @default.
• W2040389318 hasLocation W20403893184 @default.
• W2040389318 hasOpenAccess W2040389318 @default.
• W2040389318 hasPrimaryLocation W20403893181 @default.
• W2040389318 hasRelatedWork W2154967465 @default.
• W2040389318 hasRelatedWork W2361009766 @default.
• W2040389318 hasRelatedWork W2365903619 @default.
• W2040389318 hasRelatedWork W2371372815 @default.
• W2040389318 hasRelatedWork W2379497856 @default.
• W2040389318 hasRelatedWork W2410258399 @default.
• W2040389318 hasRelatedWork W2552243206 @default.
• W2040389318 hasRelatedWork W2801779377 @default.
• W2040389318 hasRelatedWork W3098122445 @default.
• W2040389318 hasRelatedWork W3111658580 @default.
• W2040389318 isParatext "false" @default.

• next