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- W2040415051 abstract "Induction of differentiation in HL-60 and U-937 leukemic cell lines, resulted in 1.5-10-fold increase in 45Ca2+ uptake. The increased 45Ca2+ uptake in the differentiating cells was inhibited by verapamil, cromolyn and amiloride. Elevation in Ca2+ uptake in differentiating cells was also demonstrated using the fluorescent probe, fura-2 acetoxymethyl ester. The increased 45Ca2+ uptake was accompanied by a decrease in ouabain-insensitive and -sensitive 86Rb+ uptake. Furthermore, correlation between the changes in these activities was observed. Modulation of extracellular pH affected differentiation: higher pH increased the extent of differentiation." @default.
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- W2040415051 date "1988-08-29" @default.
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- W2040415051 title "Differentiation-associated changes of cation-transport activities in myeloid leukemic cell lines" @default.
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- W2040415051 doi "https://doi.org/10.1016/0014-5793(88)80065-6" @default.
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