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- W2040420594 abstract "A polyclonal antisera specific for human platelet thrombospondin (TSP) has been utilized to study the biosynthesis and secretion of TSP in the M21 human melanoma cell line. Pulse-chase indirect immunoprecipitation analysis reveal that human melanoma cells rapidly synthesize and secrete this platelet alpha-granule associated glycoprotein. Topographical analysis of the melanoma cell surface by indirect immunofluorescence indicate that the TSP molecules have no obvious extracellular organization. The implications of thrombospondin synthesis in the metastatic process of melanoma are discussed." @default.
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- W2040420594 date "1989-02-01" @default.
- W2040420594 modified "2023-09-26" @default.
- W2040420594 title "Biosynthesis and secretion of thrombospondin in human melanoma cells" @default.
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- W2040420594 doi "https://doi.org/10.1016/0309-1651(89)90065-9" @default.
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