FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040423058> ?p ?o ?g. }

• W2040423058 endingPage "1200" @default.
• W2040423058 startingPage "1194" @default.
• W2040423058 abstract "The effect of a number of drugs and culture conditions on the entry into cells of a strain of poliovirus 1 (Brunende) was tested. The cells were exposed in the dark to light-sensitive, neutral red-containing virus, in the presence of the drug to be tested. Then the cells were exposed to light, transferred to normal medium, and incubated overnight. Cytopathogenic effect was measured as inhibition of [3H]leucine incorporation. Compounds that dissipate proton gradients across membranes, like monensin, protonophores, and amines, and compounds that inhibit the acidification process, such as N,N'-dicyclohexylcarbodiimide (DCCD) and tributyltin, inhibited the entry of virus, but not virus binding. This was also the case with metabolic inhibitors that deplete cells for ATP. The same compounds also inhibited the cell-induced alteration of the virus particles. When cells with surface-bound virus were exposed to low pH, the virus entered efficiently, even in the presence of monensin and DCCD. The results indicate that acidification somehow facilitates the entry of the virus RNA into the cytosol and that under normal conditions the entry occurs from intracellular acidic vesicles." @default.
• W2040423058 created "2016-06-24" @default.
• W2040423058 creator A5003589886 @default.
• W2040423058 creator A5012473938 @default.
• W2040423058 creator A5028810893 @default.
• W2040423058 date "1984-04-01" @default.
• W2040423058 modified "2023-10-17" @default.
• W2040423058 title "Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH." @default.
• W2040423058 cites W1502327274 @default.
• W2040423058 cites W1530005414 @default.
• W2040423058 cites W1542880421 @default.
• W2040423058 cites W1579621569 @default.
• W2040423058 cites W1582027534 @default.
• W2040423058 cites W1590041559 @default.
• W2040423058 cites W1591062754 @default.
• W2040423058 cites W1608617433 @default.
• W2040423058 cites W1672360053 @default.
• W2040423058 cites W1900039075 @default.
• W2040423058 cites W1905518185 @default.
• W2040423058 cites W1923572031 @default.
• W2040423058 cites W1982074683 @default.
• W2040423058 cites W1982757413 @default.
• W2040423058 cites W1994515532 @default.
• W2040423058 cites W1998950111 @default.
• W2040423058 cites W2001197606 @default.
• W2040423058 cites W2005910022 @default.
• W2040423058 cites W2005951087 @default.
• W2040423058 cites W2006849182 @default.
• W2040423058 cites W2013346825 @default.
• W2040423058 cites W2025578969 @default.
• W2040423058 cites W2030140181 @default.
• W2040423058 cites W2039628138 @default.
• W2040423058 cites W2053153019 @default.
• W2040423058 cites W2057376979 @default.
• W2040423058 cites W2090145193 @default.
• W2040423058 cites W2091791004 @default.
• W2040423058 cites W2096490954 @default.
• W2040423058 cites W2119571440 @default.
• W2040423058 cites W2125545448 @default.
• W2040423058 cites W2130012375 @default.
• W2040423058 cites W2137333901 @default.
• W2040423058 cites W66614937 @default.
• W2040423058 doi "https://doi.org/10.1083/jcb.98.4.1194" @default.
• W2040423058 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2113218" @default.
• W2040423058 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6325467" @default.
• W2040423058 hasPublicationYear "1984" @default.
• W2040423058 type Work @default.
• W2040423058 sameAs 2040423058 @default.
• W2040423058 citedByCount "108" @default.
• W2040423058 countsByYear W20404230582013 @default.
• W2040423058 countsByYear W20404230582014 @default.
• W2040423058 countsByYear W20404230582016 @default.
• W2040423058 countsByYear W20404230582020 @default.
• W2040423058 countsByYear W20404230582021 @default.
• W2040423058 countsByYear W20404230582022 @default.
• W2040423058 countsByYear W20404230582023 @default.
• W2040423058 crossrefType "journal-article" @default.
• W2040423058 hasAuthorship W2040423058A5003589886 @default.
• W2040423058 hasAuthorship W2040423058A5012473938 @default.
• W2040423058 hasAuthorship W2040423058A5028810893 @default.
• W2040423058 hasBestOaLocation W20404230581 @default.
• W2040423058 hasConcept C12554922 @default.
• W2040423058 hasConcept C130316041 @default.
• W2040423058 hasConcept C140704245 @default.
• W2040423058 hasConcept C159047783 @default.
• W2040423058 hasConcept C181199279 @default.
• W2040423058 hasConcept C2522874641 @default.
• W2040423058 hasConcept C2779631682 @default.
• W2040423058 hasConcept C2780224938 @default.
• W2040423058 hasConcept C41625074 @default.
• W2040423058 hasConcept C54355233 @default.
• W2040423058 hasConcept C55493867 @default.
• W2040423058 hasConcept C58475186 @default.
• W2040423058 hasConcept C79879829 @default.
• W2040423058 hasConcept C81885089 @default.
• W2040423058 hasConcept C86803240 @default.
• W2040423058 hasConcept C98539663 @default.
• W2040423058 hasConceptScore W2040423058C12554922 @default.
• W2040423058 hasConceptScore W2040423058C130316041 @default.
• W2040423058 hasConceptScore W2040423058C140704245 @default.
• W2040423058 hasConceptScore W2040423058C159047783 @default.
• W2040423058 hasConceptScore W2040423058C181199279 @default.
• W2040423058 hasConceptScore W2040423058C2522874641 @default.
• W2040423058 hasConceptScore W2040423058C2779631682 @default.
• W2040423058 hasConceptScore W2040423058C2780224938 @default.
• W2040423058 hasConceptScore W2040423058C41625074 @default.
• W2040423058 hasConceptScore W2040423058C54355233 @default.
• W2040423058 hasConceptScore W2040423058C55493867 @default.
• W2040423058 hasConceptScore W2040423058C58475186 @default.
• W2040423058 hasConceptScore W2040423058C79879829 @default.
• W2040423058 hasConceptScore W2040423058C81885089 @default.
• W2040423058 hasConceptScore W2040423058C86803240 @default.
• W2040423058 hasConceptScore W2040423058C98539663 @default.
• W2040423058 hasIssue "4" @default.
• W2040423058 hasLocation W20404230581 @default.
• W2040423058 hasLocation W20404230582 @default.
• W2040423058 hasLocation W20404230583 @default.
• W2040423058 hasLocation W20404230584 @default.

• next