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- W2040423718 abstract "Abstract The incubation of RNA from type 3 poliovirus (W-Fox strain) with nitrous acid caused a decrease in the average plaque size and an increase in the proportion of “small-plaque” formers in the surviving population. These “small-plaque” mutants bred true after passage in tissue culture. A reduced burst size of the treated particles was found to be the probable cause of the small plaque size. Virus isolated after the passage of several of the mutant plaque progeny pools in the human intestine showed a marked alteration from the virus fed in plaque size and reproductive capacity temperature (rct) markers (from the small, rct 40− character of the fed virus to the larger, rct 40+ character of the virus isolated). The incubation of W-Fox RNA with nitrous acid did not change the rct 40− character of the virus." @default.
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- W2040423718 title "Mutation of type 3 poliovirus with nitrous acid" @default.
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- W2040423718 doi "https://doi.org/10.1016/0042-6822(62)90086-7" @default.
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