FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040436022> ?p ?o ?g. }

• W2040436022 endingPage "520" @default.
• W2040436022 startingPage "515" @default.
• W2040436022 abstract "Background Rabeprazole is a proton pump inhibitor which is particularly suitable for use in short-term Helicobacter pylori eradication treatment. Levofloxacin-based H. pylori eradication regimens have shown good efficacy and very few side effects. Shorter treatment and absence of significant side effects should improve compliance to therapy and increase the Hp H. pylori eradication rate. Aims To evaluate the effectiveness of 2 rabeprazole-based H. pylori eradication regimens in an open-label, randomized study carried out in a clinical practice setting. Methods One hundred sixty-nine consecutive, treatment-naive patients with H. pylori infection were randomized to receive rabeprazole (20 mg, bid), levofloxacin (500 mg, bid), and tinidazole (500 mg, bid) for either 4 [4-d rabeprazole, levofloxacin, tinidazole (RLT), n=85] or 7 days (7-d RLT, n=84). Before treatment, all patients underwent upper digestive endoscopy. Cure rates were assessed by means of 13C-urea breath test. and were compared with the eradication rate obtained with standard triple therapy in our Unit (ie, 78%) and average eradication rate reported in the literature (ie, 79%). Results The intention-to-treat eradication rates were 94% [87% to 98%, 95% confidence interval (CI)] and 95% (88% to 99%, 95% CI) in the 4-day RLT and 7-day RLT regimens, respectively, whereas per-protocol eradication rates were 95% (88% to 99%, 95% CI) in the 4-day RLT and 96% (90% to 99%, 95% CI) in the 7-day RLT. Both treatment regimens obtained significantly higher eradication rates as compared with standard triple therapy. The 4-day RLT showed significantly fewer side effects. Conclusions In a clinical practice setting, both 4-day and 7-day rabeprazole, high-dose levofloxacin, tinidazole-based regimens achieved relevant H. pylori eradication rates in treatment-naive patients. The lower number of side effects makes the shorter treatment regimen preferable over the conventional 7-day treatment." @default.
• W2040436022 created "2016-06-24" @default.
• W2040436022 creator A5001660061 @default.
• W2040436022 creator A5011252301 @default.
• W2040436022 creator A5014172694 @default.
• W2040436022 creator A5027819629 @default.
• W2040436022 creator A5033284906 @default.
• W2040436022 creator A5052338213 @default.
• W2040436022 creator A5074685983 @default.
• W2040436022 creator A5086668370 @default.
• W2040436022 date "2006-07-01" @default.
• W2040436022 modified "2023-09-27" @default.
• W2040436022 title "Can Helicobacter pylori Eradication Regimens be Shortened in Clinical Practice? An Open-label, Randomized, Pilot Study of 4 and 7-day Triple Therapy With Rabeprazole, High-dose Levofloxacin, and Tinidazole" @default.
• W2040436022 cites W140788451 @default.
• W2040436022 cites W1797829304 @default.
• W2040436022 cites W1883517927 @default.
• W2040436022 cites W1964183592 @default.
• W2040436022 cites W1965187743 @default.
• W2040436022 cites W1965318798 @default.
• W2040436022 cites W1965821232 @default.
• W2040436022 cites W1970040819 @default.
• W2040436022 cites W1971649753 @default.
• W2040436022 cites W1977484825 @default.
• W2040436022 cites W1980682810 @default.
• W2040436022 cites W1981314660 @default.
• W2040436022 cites W1982183146 @default.
• W2040436022 cites W1982771665 @default.
• W2040436022 cites W1986506912 @default.
• W2040436022 cites W1995546828 @default.
• W2040436022 cites W1997321181 @default.
• W2040436022 cites W1997591774 @default.
• W2040436022 cites W2005585530 @default.
• W2040436022 cites W2013216733 @default.
• W2040436022 cites W2017383791 @default.
• W2040436022 cites W2030304316 @default.
• W2040436022 cites W2042913461 @default.
• W2040436022 cites W2049544267 @default.
• W2040436022 cites W2061938579 @default.
• W2040436022 cites W2062877992 @default.
• W2040436022 cites W2067262335 @default.
• W2040436022 cites W2071687048 @default.
• W2040436022 cites W2091731248 @default.
• W2040436022 cites W2106683700 @default.
• W2040436022 cites W2108165724 @default.
• W2040436022 cites W2108309284 @default.
• W2040436022 cites W2126492194 @default.
• W2040436022 cites W2136210283 @default.
• W2040436022 cites W2136841432 @default.
• W2040436022 cites W2139030568 @default.
• W2040436022 cites W2139373511 @default.
• W2040436022 cites W2188050548 @default.
• W2040436022 cites W2221780709 @default.
• W2040436022 cites W2614859902 @default.
• W2040436022 cites W3215248716 @default.
• W2040436022 cites W4241138581 @default.
• W2040436022 doi "https://doi.org/10.1097/00004836-200607000-00010" @default.
• W2040436022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16825934" @default.
• W2040436022 hasPublicationYear "2006" @default.
• W2040436022 type Work @default.
• W2040436022 sameAs 2040436022 @default.
• W2040436022 citedByCount "15" @default.
• W2040436022 countsByYear W20404360222012 @default.
• W2040436022 countsByYear W20404360222017 @default.
• W2040436022 countsByYear W20404360222018 @default.
• W2040436022 crossrefType "journal-article" @default.
• W2040436022 hasAuthorship W2040436022A5001660061 @default.
• W2040436022 hasAuthorship W2040436022A5011252301 @default.
• W2040436022 hasAuthorship W2040436022A5014172694 @default.
• W2040436022 hasAuthorship W2040436022A5027819629 @default.
• W2040436022 hasAuthorship W2040436022A5033284906 @default.
• W2040436022 hasAuthorship W2040436022A5052338213 @default.
• W2040436022 hasAuthorship W2040436022A5074685983 @default.
• W2040436022 hasAuthorship W2040436022A5086668370 @default.
• W2040436022 hasConcept C126322002 @default.
• W2040436022 hasConcept C141071460 @default.
• W2040436022 hasConcept C168563851 @default.
• W2040436022 hasConcept C202953159 @default.
• W2040436022 hasConcept C2775981797 @default.
• W2040436022 hasConcept C2776409635 @default.
• W2040436022 hasConcept C2777396551 @default.
• W2040436022 hasConcept C2777498785 @default.
• W2040436022 hasConcept C2778715759 @default.
• W2040436022 hasConcept C2779116819 @default.
• W2040436022 hasConcept C2780626017 @default.
• W2040436022 hasConcept C2781025758 @default.
• W2040436022 hasConcept C2781276175 @default.
• W2040436022 hasConcept C501593827 @default.
• W2040436022 hasConcept C71924100 @default.
• W2040436022 hasConcept C86803240 @default.
• W2040436022 hasConcept C89423630 @default.
• W2040436022 hasConcept C90924648 @default.
• W2040436022 hasConceptScore W2040436022C126322002 @default.
• W2040436022 hasConceptScore W2040436022C141071460 @default.
• W2040436022 hasConceptScore W2040436022C168563851 @default.
• W2040436022 hasConceptScore W2040436022C202953159 @default.
• W2040436022 hasConceptScore W2040436022C2775981797 @default.
• W2040436022 hasConceptScore W2040436022C2776409635 @default.
• W2040436022 hasConceptScore W2040436022C2777396551 @default.

• next