FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040442893> ?p ?o ?g. }

• W2040442893 endingPage "56" @default.
• W2040442893 startingPage "49" @default.
• W2040442893 abstract "We have carried out equilibrium studies of the effect of the amino acid residue difference in the primary structure of bovine cytochrome-c (b-cyt-c) and horse cyt-c (h-cyt-c) on the mechanism of their folding <--> unfolding processes at pH 6.0 and 25 degrees C. It has been observed that guanidinium chloride (GdmCl)-induced denaturation of b-cyt-c follows a two-state mechanism and that of h-cyt-c is not a two-state process. This conclusion is reached from the coincidence and non-coincidence of GdmCl-induced transition curves of bovine and horse proteins, respectively, monitored by measurements of absorbance at 405, 530 and 695 nm and circular dichroism (CD) at 222, 416 and 405 nm. These measurements on h-cyt-c in the presence of GdmCl in the concentration range 0.75-2.0 M also suggest that the protein retains all the native far-UV CD but has slightly perturbed tertiary interaction. The intermediate in the presence of these low denaturant concentrations does not have the structural characteristics of a molten globule as judged by the 8-Anilino-1-napthalene sulfonic acid (ANS) binding and near-UV CD experiments. We have also carried out thermal denaturation studies of bovine and horse cyts-c in the presence of GdmCl monitored by absorbance at 405 nm and far-UV CD at 222 nm. The heat-induced denaturation measurements in the presence of the denaturant show (1) that denaturation of b-cyt-c is a two-state process and that of h-cyt-c does not follow a two-state mechanism, and (2) that the enthalpy change on denaturation of both proteins strongly depends on GdmCl concentration." @default.
• W2040442893 created "2016-06-24" @default.
• W2040442893 creator A5035263309 @default.
• W2040442893 creator A5077513922 @default.
• W2040442893 creator A5019208896 @default.
• W2040442893 date "2003-03-01" @default.
• W2040442893 modified "2023-10-16" @default.
• W2040442893 title "Equilibrium studies of the effect of difference in sequence homology on the mechanism of denaturation of bovine and horse cytochromes-c" @default.
• W2040442893 cites W1496368635 @default.
• W2040442893 cites W1512176015 @default.
• W2040442893 cites W1521958691 @default.
• W2040442893 cites W1569015250 @default.
• W2040442893 cites W1579792554 @default.
• W2040442893 cites W1829746528 @default.
• W2040442893 cites W1964552309 @default.
• W2040442893 cites W1967305892 @default.
• W2040442893 cites W1975064838 @default.
• W2040442893 cites W1990391943 @default.
• W2040442893 cites W1997805535 @default.
• W2040442893 cites W1998347411 @default.
• W2040442893 cites W2004421107 @default.
• W2040442893 cites W2020913247 @default.
• W2040442893 cites W2034240146 @default.
• W2040442893 cites W2038263678 @default.
• W2040442893 cites W2044110936 @default.
• W2040442893 cites W2052943191 @default.
• W2040442893 cites W2068203519 @default.
• W2040442893 cites W2068683917 @default.
• W2040442893 cites W2075969041 @default.
• W2040442893 cites W2083943906 @default.
• W2040442893 cites W2086691191 @default.
• W2040442893 cites W2087509673 @default.
• W2040442893 cites W2113837017 @default.
• W2040442893 cites W2128980571 @default.
• W2040442893 cites W2145538573 @default.
• W2040442893 cites W2169950904 @default.
• W2040442893 cites W2217579908 @default.
• W2040442893 cites W2224792910 @default.
• W2040442893 cites W2298710313 @default.
• W2040442893 cites W2342124560 @default.
• W2040442893 cites W4321429423 @default.
• W2040442893 cites W46808462 @default.
• W2040442893 doi "https://doi.org/10.1016/s1570-9639(02)00548-4" @default.
• W2040442893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12637011" @default.
• W2040442893 hasPublicationYear "2003" @default.
• W2040442893 type Work @default.
• W2040442893 sameAs 2040442893 @default.
• W2040442893 citedByCount "32" @default.
• W2040442893 countsByYear W20404428932012 @default.
• W2040442893 countsByYear W20404428932013 @default.
• W2040442893 countsByYear W20404428932015 @default.
• W2040442893 countsByYear W20404428932016 @default.
• W2040442893 countsByYear W20404428932017 @default.
• W2040442893 countsByYear W20404428932018 @default.
• W2040442893 countsByYear W20404428932019 @default.
• W2040442893 countsByYear W20404428932020 @default.
• W2040442893 countsByYear W20404428932021 @default.
• W2040442893 countsByYear W20404428932022 @default.
• W2040442893 countsByYear W20404428932023 @default.
• W2040442893 crossrefType "journal-article" @default.
• W2040442893 hasAuthorship W2040442893A5019208896 @default.
• W2040442893 hasAuthorship W2040442893A5035263309 @default.
• W2040442893 hasAuthorship W2040442893A5077513922 @default.
• W2040442893 hasConcept C118493188 @default.
• W2040442893 hasConcept C133571119 @default.
• W2040442893 hasConcept C13965031 @default.
• W2040442893 hasConcept C181199279 @default.
• W2040442893 hasConcept C185592680 @default.
• W2040442893 hasConcept C2776923230 @default.
• W2040442893 hasConcept C2777654166 @default.
• W2040442893 hasConcept C28859421 @default.
• W2040442893 hasConcept C29311851 @default.
• W2040442893 hasConcept C43617362 @default.
• W2040442893 hasConcept C55493867 @default.
• W2040442893 hasConcept C62614982 @default.
• W2040442893 hasConcept C8010536 @default.
• W2040442893 hasConcept C98015330 @default.
• W2040442893 hasConceptScore W2040442893C118493188 @default.
• W2040442893 hasConceptScore W2040442893C133571119 @default.
• W2040442893 hasConceptScore W2040442893C13965031 @default.
• W2040442893 hasConceptScore W2040442893C181199279 @default.
• W2040442893 hasConceptScore W2040442893C185592680 @default.
• W2040442893 hasConceptScore W2040442893C2776923230 @default.
• W2040442893 hasConceptScore W2040442893C2777654166 @default.
• W2040442893 hasConceptScore W2040442893C28859421 @default.
• W2040442893 hasConceptScore W2040442893C29311851 @default.
• W2040442893 hasConceptScore W2040442893C43617362 @default.
• W2040442893 hasConceptScore W2040442893C55493867 @default.
• W2040442893 hasConceptScore W2040442893C62614982 @default.
• W2040442893 hasConceptScore W2040442893C8010536 @default.
• W2040442893 hasConceptScore W2040442893C98015330 @default.
• W2040442893 hasIssue "1-2" @default.
• W2040442893 hasLocation W20404428931 @default.
• W2040442893 hasLocation W20404428932 @default.
• W2040442893 hasOpenAccess W2040442893 @default.
• W2040442893 hasPrimaryLocation W20404428931 @default.
• W2040442893 hasRelatedWork W1601666612 @default.
• W2040442893 hasRelatedWork W1985158233 @default.

• next