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- W2040451621 abstract "Prostaglandin analogues have proven to be safe and effective for second trimester pregnancy terminations when given by various routes. Of these, the intra-amniotic (IA) route has proven to be safer, especially in women with medical disorders, as it causes the least occurrence of systemic side-effects. Previously, blind transabdominal IA instillation of the analogue 15-methyl PGF2 alpha was routinely possible only after 16 weeks' gestation. With the advent of ultrasound-guided techniques, it has now become possible to use the IA route for very early second trimester pregnancies. This study examines the use of single 1.5 mg 15-methyl PGF2 alpha IA injection for termination of 12-14 weeks pregnancies. Single injection resulted in successful abortion in 76.5% of women and, in the unsuccessful cases, additional prostaglandin injection resulted in successful abortion in all women within 48 hours without problems. It is therefore feasible to use ultrasound-guided IA prostaglandin injection for successful termination of early second trimester pregnancies." @default.
- W2040451621 created "2016-06-24" @default.
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- W2040451621 date "1995-02-01" @default.
- W2040451621 modified "2023-10-16" @default.
- W2040451621 title "The Feasibility of Early Second Trimester Pregnancy (12 to 14 weeks) Termination with Single Intra-Amniotic Injection of 15-Methyl PGF2α" @default.
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- W2040451621 cites W2022994058 @default.
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- W2040451621 doi "https://doi.org/10.1111/j.1479-828x.1995.tb01830.x" @default.
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