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- W2040472857 abstract "In the lacI system of Escherichia coli, X-ray mutagenesis follows a linear-quadratic curve with suppression; the survival curve is exponential. Dose fractionation leads to nearly complete repair of premutational lesions during an incubation interval of 3.5 h. Repair starts with a delay of 1.5-2 h, suggesting the involvement of an inducible repair/mutation fixation system. The dose-dependence of mutagenesis is described by a simple model assuming two hits being required. A probable explanation might be that the premutagenic lesions consist of two closely spaced lesions on the opposite strands of the DNA molecule." @default.
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- W2040472857 date "1992-01-01" @default.
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- W2040472857 title "Induction oflacI−Mutations inEscherichia ColiCells after Single and Split-dose Irradiation" @default.
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- W2040472857 doi "https://doi.org/10.1080/09553009214551611" @default.
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