SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040478873> ?p ?o ?g. }

Showing items 1 to 100 of ±105 with 100 items per page.

W2040478873 endingPage "377" @default.
W2040478873 startingPage "371" @default.
W2040478873 abstract "INTRODUÇÃO: Fatores genéticos podem desempenhar um importante papel na susceptibilidade à tuberculose (TB) ativa, e polimorfismos de base única (SNPs) em diferentes genes que codificam para citocinas têm sido descritos e associados com doenças. OBJETIVOS: Investigar o quanto polimorfismo na região promotora do gene que codifica para TNF-alfa (-238 e -308) estão associados a ocorrência de TB ativa. MÉTODOS: SNPs dentro do gene de TNF-alfa foram analisados por PCR- RFLP em dois grupos de indivíduos: pacientes com TB (n = 234) e pacientes com pneumopatias não TB (n = 113). RESULTADOS: Neste estudo, o alelo -238A esteve associado significantemente com susceptibilidade à ocorrência de TB e gravidade das formas clínicas (p = 0,00002; OR = 0,15; IC = 0,06-0,36). Por outro lado, o alelo -308A esteve associado significantemente com a proteção a outras formas de doença pulmonar (p = 0,02; OR = 1,95; IC = 1,07-3,58). CONCLUSÕES: Estes resultados preliminares sugerem a importância de estudos genéticos na ocorrência da TB. São necessários outros estudos para melhorar a compreensão sobre a patogênese do M. tb." @default.
W2040478873 created "2016-06-24" @default.
W2040478873 creator A5015660003 @default.
W2040478873 creator A5019185769 @default.
W2040478873 creator A5023055799 @default.
W2040478873 creator A5032794462 @default.
W2040478873 creator A5034148321 @default.
W2040478873 creator A5045045063 @default.
W2040478873 creator A5045848783 @default.
W2040478873 creator A5046893609 @default.
W2040478873 creator A5054659050 @default.
W2040478873 creator A5074874453 @default.
W2040478873 creator A5075880194 @default.
W2040478873 date "2004-08-01" @default.
W2040478873 modified "2023-10-17" @default.
W2040478873 title "Distribuição de Polimorfismos de Base única (SNPs) no gene de TNF-alfa (-238/-308) entre pacientes com TB e outras pneumopatias: marcadores genéticos de susceptibilidade a ocorrência de TB?" @default.
W2040478873 cites W1990097603 @default.
W2040478873 cites W1990718562 @default.
W2040478873 cites W1993764924 @default.
W2040478873 cites W1993927129 @default.
W2040478873 cites W2006671338 @default.
W2040478873 cites W2008521458 @default.
W2040478873 cites W2021274912 @default.
W2040478873 cites W2026418668 @default.
W2040478873 cites W2033935371 @default.
W2040478873 cites W2034457488 @default.
W2040478873 cites W2044720356 @default.
W2040478873 cites W2045215812 @default.
W2040478873 cites W2047374766 @default.
W2040478873 cites W2056382301 @default.
W2040478873 cites W2059543044 @default.
W2040478873 cites W2063504630 @default.
W2040478873 cites W2065791817 @default.
W2040478873 cites W2073409518 @default.
W2040478873 cites W2080334512 @default.
W2040478873 cites W2099671460 @default.
W2040478873 cites W2117931579 @default.
W2040478873 cites W2125635762 @default.
W2040478873 cites W2135254713 @default.
W2040478873 cites W2138340454 @default.
W2040478873 cites W2138528065 @default.
W2040478873 cites W2147458577 @default.
W2040478873 cites W2157376708 @default.
W2040478873 cites W2158116803 @default.
W2040478873 cites W2163410712 @default.
W2040478873 cites W4233208635 @default.
W2040478873 doi "https://doi.org/10.1590/s1806-37132004000400012" @default.
W2040478873 hasPublicationYear "2004" @default.
W2040478873 type Work @default.
W2040478873 sameAs 2040478873 @default.
W2040478873 citedByCount "10" @default.
W2040478873 countsByYear W20404788732013 @default.
W2040478873 countsByYear W20404788732015 @default.
W2040478873 countsByYear W20404788732016 @default.
W2040478873 countsByYear W20404788732019 @default.
W2040478873 crossrefType "journal-article" @default.
W2040478873 hasAuthorship W2040478873A5015660003 @default.
W2040478873 hasAuthorship W2040478873A5019185769 @default.
W2040478873 hasAuthorship W2040478873A5023055799 @default.
W2040478873 hasAuthorship W2040478873A5032794462 @default.
W2040478873 hasAuthorship W2040478873A5034148321 @default.
W2040478873 hasAuthorship W2040478873A5045045063 @default.
W2040478873 hasAuthorship W2040478873A5045848783 @default.
W2040478873 hasAuthorship W2040478873A5046893609 @default.
W2040478873 hasAuthorship W2040478873A5054659050 @default.
W2040478873 hasAuthorship W2040478873A5074874453 @default.
W2040478873 hasAuthorship W2040478873A5075880194 @default.
W2040478873 hasBestOaLocation W20404788731 @default.
W2040478873 hasConcept C104317684 @default.
W2040478873 hasConcept C135763542 @default.
W2040478873 hasConcept C153209595 @default.
W2040478873 hasConcept C153911025 @default.
W2040478873 hasConcept C54355233 @default.
W2040478873 hasConcept C71924100 @default.
W2040478873 hasConcept C86803240 @default.
W2040478873 hasConceptScore W2040478873C104317684 @default.
W2040478873 hasConceptScore W2040478873C135763542 @default.
W2040478873 hasConceptScore W2040478873C153209595 @default.
W2040478873 hasConceptScore W2040478873C153911025 @default.
W2040478873 hasConceptScore W2040478873C54355233 @default.
W2040478873 hasConceptScore W2040478873C71924100 @default.
W2040478873 hasConceptScore W2040478873C86803240 @default.
W2040478873 hasIssue "4" @default.
W2040478873 hasLocation W20404788731 @default.
W2040478873 hasLocation W20404788732 @default.
W2040478873 hasLocation W20404788733 @default.
W2040478873 hasOpenAccess W2040478873 @default.
W2040478873 hasPrimaryLocation W20404788731 @default.
W2040478873 hasRelatedWork W2037918956 @default.
W2040478873 hasRelatedWork W2041639967 @default.
W2040478873 hasRelatedWork W2049974637 @default.
W2040478873 hasRelatedWork W2053787162 @default.
W2040478873 hasRelatedWork W2161110446 @default.
W2040478873 hasRelatedWork W2360982546 @default.
W2040478873 hasRelatedWork W2371603006 @default.
W2040478873 hasRelatedWork W2382271631 @default.
W2040478873 hasRelatedWork W3194580914 @default.
W2040478873 hasRelatedWork W70073131 @default.