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- W2040487984 abstract "Extended-release naltrexone (XR-NTX) is associated with an increased number of opioid-free days, improved adherence rates in substance use disorder treatment programs, and reduced cravings and drug-seeking behaviors. There is little evidence on the predictive associations between baseline characteristics of opioid-dependent patients and XR-NTX utilization. Some studies have demonstrated better pharmacotherapy adherence and/or retention rates among non-heroin opioid users compared to heroin users. This study examines predictive associations between characteristics of patients and XR-NTX utilization, as well as participants’ urge to use opiates. Our findings suggest that XR-NTX may contribute to decreases in urges to use among both heroin and non-heroin opioid users. Non-heroin opioid users and heroin users were retained in XR-NTX treatment for comparable periods of time. However, those who identified as homeless, injected opioids (regardless of opioid-type), or were diagnosed with a mental illness were less likely to be retained in treatment with XR-NTX." @default.
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- W2040487984 date "2012-03-01" @default.
- W2040487984 modified "2023-10-16" @default.
- W2040487984 title "P.3.012 Effectiveness of naltrexone in the double blind placebo controlled clinical trial of naltrexone and guanfacine for heroin dependence" @default.
- W2040487984 doi "https://doi.org/10.1016/s0924-977x(12)70065-2" @default.
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