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- W2040492169 abstract "gamma-Tubulin is a conserved component of all microtubule-organizing centres and is required for these organelles to nucleate microtubule polymerization. However, the mechanism of nucleation is not known. In addition to its localization to organizing centres, a large pool of gamma-tubulin exists in the cytoplasm in a complex with other proteins. The size of the gamma-tubulin complex and number of associated proteins vary among organisms, and the functional significance of these differences is unknown. Recently, the nature of these gamma-tubulin complexes has been explored in different organisms, and this has led us closer to a molecular understanding of microtubule nucleation." @default.
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- W2040492169 date "1999-09-01" @default.
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- W2040492169 title "γ-Tubulin complexes: size does matter" @default.
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- W2040492169 doi "https://doi.org/10.1016/s0962-8924(99)01621-9" @default.
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