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• W2040500512 abstract "New ionic and amphiphilic polysaccharide-based hydrogels were synthesized and evaluated for controlled release entrapment applications. The starting polysaccharide (pullulan) was first carboxymethylated to provide ionic derivatives. The hydrogels were then obtained by cross-linking carboxymethylpullulan with adipic acid dihydrazide in water in the presence of 1-ethyl-3-[3-(dimethylamino)-propyl]carbodiimide hydrochloride (EDCI) as reagent. A set of hydrogels differing by their cross-linking densities was prepared and their degree of swelling were measured in water and in the presence of sodium chloride (0.1 mol L−1). The entrapment capacity of hydrogels was estimated using two probe molecules: methylene blue, a cationic dye with a high affinity with negatively charged compounds and coomassy brilliant blue, a molecule having a marked amphiphilic character. The ionic and/or amphiphilic properties of the hydrogels were then demonstrated by their capacity or not to entrap these molecules." @default.
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• W2040500512 date "2006-02-01" @default.
• W2040500512 modified "2023-10-13" @default.
• W2040500512 title "Carboxymethylpullulan hydrogels with a ionic and/or amphiphilic behavior: Swelling properties and entrapment of cationic and/or hydrophobic molecules" @default.
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• W2040500512 doi "https://doi.org/10.1016/j.colsurfa.2005.08.045" @default.
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