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W2040503109 abstract "Relaxin (RLN) is a naturally occurring hormone that is known to modulate connective tissue remodeling in the uterus and cervix. Our goal was to investigate the role of RLN in endometrial cancer. RLN expression was evaluated using immunohistochemistry in 57 samples of invasive endometrial carcinoma (EC) and 10 benign endometria. 67% of high-stage (III/IV) tumors demonstrated strong RLN expression compared to 37% of low-stage (I/II) cases. Strong RLN expression associated significantly with high-grade and depth of myometrial invasion. Notably, strong RLN expression was associated with a significantly shorter overall survival (p" @default.
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W2040503109 date "2006-01-16" @default.
W2040503109 modified "2023-09-26" @default.
W2040503109 title "The role of relaxin in endometrial cancer" @default.
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W2040503109 doi "https://doi.org/10.4161/cbt.5.1.2289" @default.
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