Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040503670> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2040503670 endingPage "2703" @default.
- W2040503670 startingPage "2697" @default.
- W2040503670 abstract "Ornithine decarboxylase in rat ovary is stimulated 5- to 10-fold by a subcutaneous injection of luteinizing hormone (LH) or human chorionic gonadotrophin (HCG). A peak is observed between 3 and 5 hr after which the enzyme activity declines rapidly. The pattern of enzyme response to hormonal administration is similar to that observed during late proestrus. S-adenosylmethionine decarboxylase is not altered during this period or after administration of LH or HCG. Cycloheximide administered in vivo markedly reduced ovarian ornithine decarboxylase within 15 min, suggesting that the turnover of this enzyme in the ovary is very rapid. When injected immediately prior to HCG, cycloheximide also prevented the rise in ornithine decarboxylase activity. High doses of actinomycin d were also effective in blocking the response to HCG. Ornithine decarboxylase responds to a single injection of HCG at all stages of the estrus cycle, but repeated injections do not prevent the decline in enzyme activity occurring between 5 and 7 hr. Anti-HCG injected immediately before the primary hormone completely inhbited the rise in ornithine decarboxylase, but when given 1 hr after the primary injection, it was ineffective. It is suggested that these characteristics of ornithine decarboxylase, i.e. high rate of turnover, rapid induction and the inability of repeated hormone injections to prevent the eventual decline of enzyme activity, ensure that the increase in the formation of putrescine during proestrus is restricted to a relatively narrow time period, thus supporting the view that putrescine may have a specific role in the regulation of protein and RNA synthesis involved in the early phase of LH action on the ovary." @default.
- W2040503670 created "2016-06-24" @default.
- W2040503670 creator A5032075717 @default.
- W2040503670 creator A5033827654 @default.
- W2040503670 date "1974-10-01" @default.
- W2040503670 modified "2023-09-25" @default.
- W2040503670 title "Induction of ornithine decarboxylase in rat ovary after administration of luteinizing hormone or human chorionic gonadotrophin" @default.
- W2040503670 cites W155569352 @default.
- W2040503670 cites W1964837021 @default.
- W2040503670 cites W1975873982 @default.
- W2040503670 cites W1991997009 @default.
- W2040503670 cites W2002236269 @default.
- W2040503670 cites W2008513433 @default.
- W2040503670 cites W2009031964 @default.
- W2040503670 cites W2011902932 @default.
- W2040503670 cites W2017965458 @default.
- W2040503670 cites W2028540596 @default.
- W2040503670 cites W2029111079 @default.
- W2040503670 cites W2054504219 @default.
- W2040503670 cites W2070077751 @default.
- W2040503670 cites W2077678162 @default.
- W2040503670 cites W2078480138 @default.
- W2040503670 cites W2118970663 @default.
- W2040503670 cites W2134119740 @default.
- W2040503670 cites W2168941921 @default.
- W2040503670 cites W594429199 @default.
- W2040503670 doi "https://doi.org/10.1016/0006-2952(74)90040-9" @default.
- W2040503670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4472586" @default.
- W2040503670 hasPublicationYear "1974" @default.
- W2040503670 type Work @default.
- W2040503670 sameAs 2040503670 @default.
- W2040503670 citedByCount "32" @default.
- W2040503670 countsByYear W20405036702018 @default.
- W2040503670 countsByYear W20405036702021 @default.
- W2040503670 crossrefType "journal-article" @default.
- W2040503670 hasAuthorship W2040503670A5032075717 @default.
- W2040503670 hasAuthorship W2040503670A5033827654 @default.
- W2040503670 hasConcept C108905728 @default.
- W2040503670 hasConcept C121289238 @default.
- W2040503670 hasConcept C126322002 @default.
- W2040503670 hasConcept C134018914 @default.
- W2040503670 hasConcept C181199279 @default.
- W2040503670 hasConcept C185592680 @default.
- W2040503670 hasConcept C1998276 @default.
- W2040503670 hasConcept C2775948956 @default.
- W2040503670 hasConcept C2776796294 @default.
- W2040503670 hasConcept C2777167505 @default.
- W2040503670 hasConcept C2777468819 @default.
- W2040503670 hasConcept C2778128677 @default.
- W2040503670 hasConcept C2778324911 @default.
- W2040503670 hasConcept C2778575703 @default.
- W2040503670 hasConcept C3675279 @default.
- W2040503670 hasConcept C515207424 @default.
- W2040503670 hasConcept C55493867 @default.
- W2040503670 hasConcept C71315377 @default.
- W2040503670 hasConcept C71924100 @default.
- W2040503670 hasConcept C86803240 @default.
- W2040503670 hasConceptScore W2040503670C108905728 @default.
- W2040503670 hasConceptScore W2040503670C121289238 @default.
- W2040503670 hasConceptScore W2040503670C126322002 @default.
- W2040503670 hasConceptScore W2040503670C134018914 @default.
- W2040503670 hasConceptScore W2040503670C181199279 @default.
- W2040503670 hasConceptScore W2040503670C185592680 @default.
- W2040503670 hasConceptScore W2040503670C1998276 @default.
- W2040503670 hasConceptScore W2040503670C2775948956 @default.
- W2040503670 hasConceptScore W2040503670C2776796294 @default.
- W2040503670 hasConceptScore W2040503670C2777167505 @default.
- W2040503670 hasConceptScore W2040503670C2777468819 @default.
- W2040503670 hasConceptScore W2040503670C2778128677 @default.
- W2040503670 hasConceptScore W2040503670C2778324911 @default.
- W2040503670 hasConceptScore W2040503670C2778575703 @default.
- W2040503670 hasConceptScore W2040503670C3675279 @default.
- W2040503670 hasConceptScore W2040503670C515207424 @default.
- W2040503670 hasConceptScore W2040503670C55493867 @default.
- W2040503670 hasConceptScore W2040503670C71315377 @default.
- W2040503670 hasConceptScore W2040503670C71924100 @default.
- W2040503670 hasConceptScore W2040503670C86803240 @default.
- W2040503670 hasIssue "19" @default.
- W2040503670 hasLocation W20405036701 @default.
- W2040503670 hasLocation W20405036702 @default.
- W2040503670 hasOpenAccess W2040503670 @default.
- W2040503670 hasPrimaryLocation W20405036701 @default.
- W2040503670 hasRelatedWork W2006086030 @default.
- W2040503670 hasRelatedWork W2037126332 @default.
- W2040503670 hasRelatedWork W2040503670 @default.
- W2040503670 hasRelatedWork W2050902768 @default.
- W2040503670 hasRelatedWork W2054416664 @default.
- W2040503670 hasRelatedWork W2076983860 @default.
- W2040503670 hasRelatedWork W2092478584 @default.
- W2040503670 hasRelatedWork W2113340095 @default.
- W2040503670 hasRelatedWork W2226159200 @default.
- W2040503670 hasRelatedWork W2345067921 @default.
- W2040503670 hasVolume "23" @default.
- W2040503670 isParatext "false" @default.
- W2040503670 isRetracted "false" @default.
- W2040503670 magId "2040503670" @default.
- W2040503670 workType "article" @default.