Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040506688> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2040506688 endingPage "796" @default.
- W2040506688 startingPage "791" @default.
- W2040506688 abstract "The utility of using an endurance test as well as a maximal exercise test to assess the effect of amlodipine, a dihydropyridine calcium antagonist, was evaluated in 16 patients with angina pectoris. Amlodipine, 10 mg/day, was compared with placebo in a double blind crossover study. After a 2 week single blind placebo period, patients entered a double blind crossover phase alternating between 4 weeks of placebo and 4 weeks of amlodipine. The two 4 week periods were separated by a 1 week single blind placebo washout period. The efficacy of drug therapy was assessed by frequency of angina, nitroglycerin consumption, peak oxygen consumption during a maximal treadmill exercise test and endurance time during a separate exercise test performed at 70% of the peak work capacity determined before randomization. There was a reduction in angina frequency during the double blind placebo and amlodipine studies (single blind placebo 14 +/- 2 episodes/2 weeks, double blind placebo 7 +/- 2 episodes/2 weeks [p less than 0.005], amlodipine 6 +/- 3 episodes/2 weeks, [p less than 0.005]), whereas nitroglycerin consumption was reduced with amlodipine (single blind placebo 12 +/- 4 tablets/2 weeks, double blind placebo 8 +/- 3 tablets/2 weeks, amlodipine 5 +/- 3 tablets/2 weeks [p less than 0.01]). Amlodipine produced a significant increase in peak oxygen consumption (single blind placebo 18.7 +/- 1.1 ml/kg per min, double blind placebo 18.2 +/- 1.8 ml/kg per min, amlodipine 20.4 +/- 1.6 ml/kg per min [p less than 0.05]) and endurance time (single blind placebo 15.2 +/- 1.5 min, double blind placebo 15.8 +/- 2.1 min, amlodipine 20.2 +/- 2.5 min [p less than 0.005]).(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2040506688 created "2016-06-24" @default.
- W2040506688 creator A5013723901 @default.
- W2040506688 creator A5014399010 @default.
- W2040506688 creator A5069804672 @default.
- W2040506688 date "1988-01-01" @default.
- W2040506688 modified "2023-09-26" @default.
- W2040506688 title "Endurance testing for evaluation of antianginal therapy with amlodipine, a calcium channel blocking agent" @default.
- W2040506688 cites W1911932872 @default.
- W2040506688 cites W1934028002 @default.
- W2040506688 cites W1999366249 @default.
- W2040506688 cites W2020470301 @default.
- W2040506688 cites W2036116109 @default.
- W2040506688 cites W2036217273 @default.
- W2040506688 cites W2037915161 @default.
- W2040506688 cites W2073530787 @default.
- W2040506688 cites W2075641411 @default.
- W2040506688 cites W2077886785 @default.
- W2040506688 cites W2142732273 @default.
- W2040506688 cites W4249783448 @default.
- W2040506688 doi "https://doi.org/10.1016/0735-1097(88)90323-3" @default.
- W2040506688 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2969930" @default.
- W2040506688 hasPublicationYear "1988" @default.
- W2040506688 type Work @default.
- W2040506688 sameAs 2040506688 @default.
- W2040506688 citedByCount "19" @default.
- W2040506688 countsByYear W20405066882012 @default.
- W2040506688 countsByYear W20405066882015 @default.
- W2040506688 crossrefType "journal-article" @default.
- W2040506688 hasAuthorship W2040506688A5013723901 @default.
- W2040506688 hasAuthorship W2040506688A5014399010 @default.
- W2040506688 hasAuthorship W2040506688A5069804672 @default.
- W2040506688 hasBestOaLocation W20405066881 @default.
- W2040506688 hasConcept C126322002 @default.
- W2040506688 hasConcept C130049864 @default.
- W2040506688 hasConcept C142724271 @default.
- W2040506688 hasConcept C164705383 @default.
- W2040506688 hasConcept C204243189 @default.
- W2040506688 hasConcept C204787440 @default.
- W2040506688 hasConcept C27081682 @default.
- W2040506688 hasConcept C2777953023 @default.
- W2040506688 hasConcept C2778425758 @default.
- W2040506688 hasConcept C2779646130 @default.
- W2040506688 hasConcept C2991744798 @default.
- W2040506688 hasConcept C42219234 @default.
- W2040506688 hasConcept C500558357 @default.
- W2040506688 hasConcept C535046627 @default.
- W2040506688 hasConcept C71924100 @default.
- W2040506688 hasConcept C84393581 @default.
- W2040506688 hasConcept C87813604 @default.
- W2040506688 hasConceptScore W2040506688C126322002 @default.
- W2040506688 hasConceptScore W2040506688C130049864 @default.
- W2040506688 hasConceptScore W2040506688C142724271 @default.
- W2040506688 hasConceptScore W2040506688C164705383 @default.
- W2040506688 hasConceptScore W2040506688C204243189 @default.
- W2040506688 hasConceptScore W2040506688C204787440 @default.
- W2040506688 hasConceptScore W2040506688C27081682 @default.
- W2040506688 hasConceptScore W2040506688C2777953023 @default.
- W2040506688 hasConceptScore W2040506688C2778425758 @default.
- W2040506688 hasConceptScore W2040506688C2779646130 @default.
- W2040506688 hasConceptScore W2040506688C2991744798 @default.
- W2040506688 hasConceptScore W2040506688C42219234 @default.
- W2040506688 hasConceptScore W2040506688C500558357 @default.
- W2040506688 hasConceptScore W2040506688C535046627 @default.
- W2040506688 hasConceptScore W2040506688C71924100 @default.
- W2040506688 hasConceptScore W2040506688C84393581 @default.
- W2040506688 hasConceptScore W2040506688C87813604 @default.
- W2040506688 hasIssue "3" @default.
- W2040506688 hasLocation W20405066881 @default.
- W2040506688 hasLocation W20405066882 @default.
- W2040506688 hasOpenAccess W2040506688 @default.
- W2040506688 hasPrimaryLocation W20405066881 @default.
- W2040506688 hasRelatedWork W1984223073 @default.
- W2040506688 hasRelatedWork W2010251665 @default.
- W2040506688 hasRelatedWork W2012622927 @default.
- W2040506688 hasRelatedWork W2040506688 @default.
- W2040506688 hasRelatedWork W2075930929 @default.
- W2040506688 hasRelatedWork W2076017222 @default.
- W2040506688 hasRelatedWork W2077168757 @default.
- W2040506688 hasRelatedWork W2132710482 @default.
- W2040506688 hasRelatedWork W2227654656 @default.
- W2040506688 hasRelatedWork W2463113651 @default.
- W2040506688 hasVolume "12" @default.
- W2040506688 isParatext "false" @default.
- W2040506688 isRetracted "false" @default.
- W2040506688 magId "2040506688" @default.
- W2040506688 workType "article" @default.