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- W2040522867 abstract "In this article we provide a comprehensive literature review on the in vivo assessment of use-dependant brain structure changes in humans using magnetic resonance imaging (MRI) and computational anatomy. We highlight the recent findings in this field that allow the uncovering of the basic principles behind brain plasticity in light of the existing theoretical models at various scales of observation. Given the current lack of in-depth understanding of the neurobiological basis of brain structure changes we emphasize the necessity of a paradigm shift in the investigation and interpretation of use-dependent brain plasticity. Novel quantitative MRI acquisition techniques provide access to brain tissue microstructural properties (e.g., myelin, iron, and water content) in-vivo, thereby allowing unprecedented specific insights into the mechanisms underlying brain plasticity. These quantitative MRI techniques require novel methods for image processing and analysis of longitudinal data allowing for straightforward interpretation and causality inferences." @default.
- W2040522867 created "2016-06-24" @default.
- W2040522867 creator A5000783507 @default.
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- W2040522867 date "2014-06-27" @default.
- W2040522867 modified "2023-09-23" @default.
- W2040522867 title "Computational anatomy for studying use-dependant brain plasticity" @default.
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- W2040522867 doi "https://doi.org/10.3389/fnhum.2014.00380" @default.
- W2040522867 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4072968" @default.
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