FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040546819> ?p ?o ?g. }

• W2040546819 endingPage "982" @default.
• W2040546819 startingPage "975" @default.
• W2040546819 abstract "Background Early life stress (ELS) is linked to adult psychopathology and may contribute to long-term brain alterations, as suggested by studies of women who suffered childhood sexual abuse. We examine whether reported adverse ELS defined as stressful and/or traumatic adverse childhood events (ACEs) is associated with smaller limbic and basal ganglia volumes. Method 265 healthy Australian men and women without psychopathology or brain disorders were studied. ACEs were assessed by the ELSQ and current emotional state by the DASS. Anterior cingulate cortex (ACC), hippocampus, amygdala, and caudate nucleus volumes were measured from T1-weighted MRI. Analyses examined ROI volumetric associations with reported ACEs and DASS scores. Results Participants with greater than two ACEs had smaller ACC and caudate nuclei than those without ACEs. A significant association between total ACEs and ROI volumes for these structures was observed. Regression analysis also revealed that ELS was more strongly associated than current emotional state (DASS) with these ROI volumes. Conclusions Reported ELS is associated with smaller ACC and caudate volumes, but not the hippocampal or amygdala volumes. The reasons for these brain effects are not entirely clear, but may reflect the influence of early stress and traumatic events on the developing brain. Early life stress (ELS) is linked to adult psychopathology and may contribute to long-term brain alterations, as suggested by studies of women who suffered childhood sexual abuse. We examine whether reported adverse ELS defined as stressful and/or traumatic adverse childhood events (ACEs) is associated with smaller limbic and basal ganglia volumes. 265 healthy Australian men and women without psychopathology or brain disorders were studied. ACEs were assessed by the ELSQ and current emotional state by the DASS. Anterior cingulate cortex (ACC), hippocampus, amygdala, and caudate nucleus volumes were measured from T1-weighted MRI. Analyses examined ROI volumetric associations with reported ACEs and DASS scores. Participants with greater than two ACEs had smaller ACC and caudate nuclei than those without ACEs. A significant association between total ACEs and ROI volumes for these structures was observed. Regression analysis also revealed that ELS was more strongly associated than current emotional state (DASS) with these ROI volumes. Reported ELS is associated with smaller ACC and caudate volumes, but not the hippocampal or amygdala volumes. The reasons for these brain effects are not entirely clear, but may reflect the influence of early stress and traumatic events on the developing brain." @default.
• W2040546819 created "2016-06-24" @default.
• W2040546819 creator A5007566739 @default.
• W2040546819 creator A5013689337 @default.
• W2040546819 creator A5021789074 @default.
• W2040546819 creator A5022396797 @default.
• W2040546819 creator A5025528747 @default.
• W2040546819 creator A5030835336 @default.
• W2040546819 creator A5034451393 @default.
• W2040546819 creator A5035290107 @default.
• W2040546819 creator A5041813529 @default.
• W2040546819 creator A5058115883 @default.
• W2040546819 creator A5072862594 @default.
• W2040546819 creator A5075320351 @default.
• W2040546819 creator A5076777565 @default.
• W2040546819 creator A5080434783 @default.
• W2040546819 creator A5083848316 @default.
• W2040546819 creator A5087169102 @default.
• W2040546819 date "2006-05-01" @default.
• W2040546819 modified "2023-10-17" @default.
• W2040546819 title "Early Life Stress and Morphometry of the Adult Anterior Cingulate Cortex and Caudate Nuclei" @default.
• W2040546819 cites W1495475554 @default.
• W2040546819 cites W1571434348 @default.
• W2040546819 cites W1663918944 @default.
• W2040546819 cites W1694363227 @default.
• W2040546819 cites W170792860 @default.
• W2040546819 cites W1966372902 @default.
• W2040546819 cites W1984500369 @default.
• W2040546819 cites W1985891447 @default.
• W2040546819 cites W1986582521 @default.
• W2040546819 cites W1987984085 @default.
• W2040546819 cites W1988875934 @default.
• W2040546819 cites W1990001362 @default.
• W2040546819 cites W1990379520 @default.
• W2040546819 cites W1995225454 @default.
• W2040546819 cites W2002791710 @default.
• W2040546819 cites W2004806079 @default.
• W2040546819 cites W2005533083 @default.
• W2040546819 cites W2007181889 @default.
• W2040546819 cites W2010106299 @default.
• W2040546819 cites W2010222763 @default.
• W2040546819 cites W2011812102 @default.
• W2040546819 cites W2011904866 @default.
• W2040546819 cites W2017506121 @default.
• W2040546819 cites W2020291009 @default.
• W2040546819 cites W2020961462 @default.
• W2040546819 cites W2025911957 @default.
• W2040546819 cites W2027483750 @default.
• W2040546819 cites W2031854617 @default.
• W2040546819 cites W2034824117 @default.
• W2040546819 cites W2035445462 @default.
• W2040546819 cites W2037238565 @default.
• W2040546819 cites W2040937137 @default.
• W2040546819 cites W2041326891 @default.
• W2040546819 cites W2041914100 @default.
• W2040546819 cites W2049865257 @default.
• W2040546819 cites W2053499397 @default.
• W2040546819 cites W2054092091 @default.
• W2040546819 cites W2054808935 @default.
• W2040546819 cites W2058046532 @default.
• W2040546819 cites W2058463249 @default.
• W2040546819 cites W2059560856 @default.
• W2040546819 cites W2060390773 @default.
• W2040546819 cites W2063175652 @default.
• W2040546819 cites W2064212981 @default.
• W2040546819 cites W2064323651 @default.
• W2040546819 cites W2066095975 @default.
• W2040546819 cites W2075090826 @default.
• W2040546819 cites W2075836208 @default.
• W2040546819 cites W2076044491 @default.
• W2040546819 cites W2076625962 @default.
• W2040546819 cites W2078009077 @default.
• W2040546819 cites W2082327542 @default.
• W2040546819 cites W2082861673 @default.
• W2040546819 cites W2085467925 @default.
• W2040546819 cites W2089031800 @default.
• W2040546819 cites W2090123983 @default.
• W2040546819 cites W2091880444 @default.
• W2040546819 cites W2092058928 @default.
• W2040546819 cites W2094054262 @default.
• W2040546819 cites W2096218321 @default.
• W2040546819 cites W2096671017 @default.
• W2040546819 cites W2098631889 @default.
• W2040546819 cites W2099652807 @default.
• W2040546819 cites W2101562854 @default.
• W2040546819 cites W2105291430 @default.
• W2040546819 cites W2109301184 @default.
• W2040546819 cites W2110445621 @default.
• W2040546819 cites W2114959084 @default.
• W2040546819 cites W2118421222 @default.
• W2040546819 cites W2118439943 @default.
• W2040546819 cites W2119848633 @default.
• W2040546819 cites W2120486228 @default.
• W2040546819 cites W2123197173 @default.
• W2040546819 cites W2126041442 @default.
• W2040546819 cites W2126863368 @default.
• W2040546819 cites W2128472215 @default.
• W2040546819 cites W2131837368 @default.

• next