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- W2040572397 abstract "The monitoring of cyclosporine levels in whole blood and serum has become a routine procedure for the post-transplant management of immunosuppression. We have developed fluorescence polarization immunoassays for cyclosporine in whole blood and in serum using a monoclonal antibody. These assays are fast (20 determinations in less than 22 min), sensitive (25 μg/L for whole blood samples and 10 μg/L for serum samples), and precise (CV less than 7% in both assays). Cross-reactivities with AM1 (Metabolite 17) and AM4N (Metabolite 21) are less than 8.5 and 2.5%, respectively, for both assays." @default.
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- W2040572397 date "1991-02-01" @default.
- W2040572397 modified "2023-09-27" @default.
- W2040572397 title "Cyclosporine monitoring by fluorescence polarization immunoassay" @default.
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- W2040572397 doi "https://doi.org/10.1016/0009-9120(91)90210-6" @default.
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