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- W2040576725 endingPage "147" @default.
- W2040576725 startingPage "139" @default.
- W2040576725 abstract "Drug delivery systems involve technology designed to maximize therapeutic efficacy of drugs by controlling their biodistribution profile. In order to optimize a function of the delivery systems, their biodistribution characteristics should be systematically understood. Pharmacokinetic analysis based on the clearance concepts provides quantitative information of the biodistribution, which can be related to physicochemical properties of the delivery system. Various delivery systems including macromolecular drug conjugates, chemically or genetically modified proteins, and particulate drug carriers have been designed and developed so far. In this article, we review physiological and pharmacokinetic implications of the delivery systems." @default.
- W2040576725 created "2016-06-24" @default.
- W2040576725 creator A5082694156 @default.
- W2040576725 creator A5091285288 @default.
- W2040576725 date "2013-01-01" @default.
- W2040576725 modified "2023-10-08" @default.
- W2040576725 title "Pharmacokinetic considerations for targeted drug delivery" @default.
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