FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040576892> ?p ?o ?g. }

• W2040576892 endingPage "1293" @default.
• W2040576892 startingPage "1283" @default.
• W2040576892 abstract "Macrophages are reservoirs for replicating mycobacterium during tuberculosis (TB) infections. In this study, small molecules to be developed as anti-tubercular treatments were investigated for their ability to kill intracellular bacteria in in vitro macrophage models. High-content imaging technologies offer a high-throughput method to quantify a drug’s ability to inhibit Mycobacterium tuberculosis intracellular invasion and multiplication in host cells. Dedicated image analysis enables the automated quantification of infected macrophages, and compounds that inhibit mycobacteria proliferation can be tested using this method. Furthermore, the implementation of the assay in 384-well microtiter plates combined with automated image acquisition and analysis allows large-scale screening of compound libraries in M. tuberculosis-infected macrophages. Here we describe a high-throughput and high-content workflow and detail its utility for the development of new TB drugs." @default.
• W2040576892 created "2016-06-24" @default.
• W2040576892 creator A5001249714 @default.
• W2040576892 creator A5034111423 @default.
• W2040576892 creator A5074708936 @default.
• W2040576892 creator A5078142118 @default.
• W2040576892 creator A5080658097 @default.
• W2040576892 date "2010-08-01" @default.
• W2040576892 modified "2023-10-02" @default.
• W2040576892 title "High-content imaging of <i>Mycobacterium tuberculosis</i>-infected macrophages: an <i>in vitro</i> model for tuberculosis drug discovery" @default.
• W2040576892 cites W1548106543 @default.
• W2040576892 cites W1798204859 @default.
• W2040576892 cites W1969623044 @default.
• W2040576892 cites W1973577139 @default.
• W2040576892 cites W1986027775 @default.
• W2040576892 cites W1988600626 @default.
• W2040576892 cites W1991001144 @default.
• W2040576892 cites W2016388450 @default.
• W2040576892 cites W2028561329 @default.
• W2040576892 cites W2049798802 @default.
• W2040576892 cites W2053534534 @default.
• W2040576892 cites W2064097501 @default.
• W2040576892 cites W2064953244 @default.
• W2040576892 cites W2091442643 @default.
• W2040576892 cites W2102208377 @default.
• W2040576892 cites W2115477132 @default.
• W2040576892 cites W2127347661 @default.
• W2040576892 cites W2164969270 @default.
• W2040576892 doi "https://doi.org/10.4155/fmc.10.223" @default.
• W2040576892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21426019" @default.
• W2040576892 hasPublicationYear "2010" @default.
• W2040576892 type Work @default.
• W2040576892 sameAs 2040576892 @default.
• W2040576892 citedByCount "55" @default.
• W2040576892 countsByYear W20405768922012 @default.
• W2040576892 countsByYear W20405768922013 @default.
• W2040576892 countsByYear W20405768922014 @default.
• W2040576892 countsByYear W20405768922015 @default.
• W2040576892 countsByYear W20405768922016 @default.
• W2040576892 countsByYear W20405768922017 @default.
• W2040576892 countsByYear W20405768922018 @default.
• W2040576892 countsByYear W20405768922019 @default.
• W2040576892 countsByYear W20405768922020 @default.
• W2040576892 countsByYear W20405768922021 @default.
• W2040576892 countsByYear W20405768922022 @default.
• W2040576892 countsByYear W20405768922023 @default.
• W2040576892 crossrefType "journal-article" @default.
• W2040576892 hasAuthorship W2040576892A5001249714 @default.
• W2040576892 hasAuthorship W2040576892A5034111423 @default.
• W2040576892 hasAuthorship W2040576892A5074708936 @default.
• W2040576892 hasAuthorship W2040576892A5078142118 @default.
• W2040576892 hasAuthorship W2040576892A5080658097 @default.
• W2040576892 hasConcept C142724271 @default.
• W2040576892 hasConcept C1491633281 @default.
• W2040576892 hasConcept C153726182 @default.
• W2040576892 hasConcept C157044486 @default.
• W2040576892 hasConcept C202751555 @default.
• W2040576892 hasConcept C2777975735 @default.
• W2040576892 hasConcept C2779244956 @default.
• W2040576892 hasConcept C2780374374 @default.
• W2040576892 hasConcept C2781069245 @default.
• W2040576892 hasConcept C523546767 @default.
• W2040576892 hasConcept C54355233 @default.
• W2040576892 hasConcept C55493867 @default.
• W2040576892 hasConcept C60644358 @default.
• W2040576892 hasConcept C71924100 @default.
• W2040576892 hasConcept C74187038 @default.
• W2040576892 hasConcept C79879829 @default.
• W2040576892 hasConcept C86803240 @default.
• W2040576892 hasConcept C89423630 @default.
• W2040576892 hasConcept C95444343 @default.
• W2040576892 hasConceptScore W2040576892C142724271 @default.
• W2040576892 hasConceptScore W2040576892C1491633281 @default.
• W2040576892 hasConceptScore W2040576892C153726182 @default.
• W2040576892 hasConceptScore W2040576892C157044486 @default.
• W2040576892 hasConceptScore W2040576892C202751555 @default.
• W2040576892 hasConceptScore W2040576892C2777975735 @default.
• W2040576892 hasConceptScore W2040576892C2779244956 @default.
• W2040576892 hasConceptScore W2040576892C2780374374 @default.
• W2040576892 hasConceptScore W2040576892C2781069245 @default.
• W2040576892 hasConceptScore W2040576892C523546767 @default.
• W2040576892 hasConceptScore W2040576892C54355233 @default.
• W2040576892 hasConceptScore W2040576892C55493867 @default.
• W2040576892 hasConceptScore W2040576892C60644358 @default.
• W2040576892 hasConceptScore W2040576892C71924100 @default.
• W2040576892 hasConceptScore W2040576892C74187038 @default.
• W2040576892 hasConceptScore W2040576892C79879829 @default.
• W2040576892 hasConceptScore W2040576892C86803240 @default.
• W2040576892 hasConceptScore W2040576892C89423630 @default.
• W2040576892 hasConceptScore W2040576892C95444343 @default.
• W2040576892 hasIssue "8" @default.
• W2040576892 hasLocation W20405768921 @default.
• W2040576892 hasLocation W20405768922 @default.
• W2040576892 hasOpenAccess W2040576892 @default.
• W2040576892 hasPrimaryLocation W20405768921 @default.
• W2040576892 hasRelatedWork W1973577139 @default.
• W2040576892 hasRelatedWork W1994997046 @default.
• W2040576892 hasRelatedWork W2026991602 @default.

• next