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• W2040582159 abstract "Susceptibility to migraine is determined by genetic factors and is therefore subject to the forces of natural selection. Migraine is a common and ancient disorder whose prevalence may be increasing, suggesting that a migraine-prone nervous system may be associated with reproductive or survival advantages. Five evolutionary explanations are reviewed that might account for the persistence of migraine: (i) migraine as a defence mechanism; (ii) migraine as a result of conflict with other organisms; (iii) migraine as result of novel environmental factors; (iv) migraine as a trade-off between genetic harms and benefits; and (v) migraine as a design constraint. An evolutionary perspective on migraine allows the generation of important hypotheses about the disorder and suggests rewarding possibilities for further research." @default.
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• W2040582159 date "2002-10-01" @default.
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• W2040582159 title "What is the Evolutionary Advantage of Migraine?" @default.
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• W2040582159 doi "https://doi.org/10.1046/j.1468-2982.2002.00437.x" @default.
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