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• W2040583755 startingPage "235" @default.
• W2040583755 abstract "Because of the poor prognosis for patients with locally advanced and metastatic esophageal, gastroesophageal junction and gastric cancers, increasing attention has focused on the integration of targeted agents into current therapies. The molecular targets of these agents include epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF) or its receptor, cyclooxygenase-2 (COX-2), mammalian target of rapamycin (mTOR) and components and regulators of the cell cycle. In this review article, we briefly discuss pre-clinical data and the rationale for targeting these pathways and summarize the results of clinical trials to-date, including completed and ongoing phase III evaluations." @default.
• W2040583755 created "2016-06-24" @default.
• W2040583755 creator A5035865205 @default.
• W2040583755 creator A5068026508 @default.
• W2040583755 date "2010-05-01" @default.
• W2040583755 modified "2023-10-14" @default.
• W2040583755 title "Esophagogastric cancer: Targeted agents" @default.
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