FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040584700> ?p ?o ?g. }

• W2040584700 endingPage "263" @default.
• W2040584700 startingPage "257" @default.
• W2040584700 abstract "Humans can come into contact with chlorine gas during short-term, high-level exposures due to traffic or rail accidents, spills, or other disasters. By contrast, workplace and public (swimming pools, etc.) exposures are more frequently long-term, low-level exposures, occasionally punctuated by unintentional transient increases. Acute exposures can result in symptoms of acute airway obstruction including wheezing, cough, chest tightness, and/or dyspnea. These findings are fairly nonspecific, and might be present after exposures to a number of inhaled chemical irritants. Clinical signs, including hypoxemia, wheezes, rales, and/or abnormal chest radiographs may be present. More severely affected individuals may suffer acute lung injury (ALI) and/or acute respiratory distress syndrome (ARDS). Up to 1% of exposed individuals die. Humidified oxygen and inhaled beta-adrenergic agents are appropriate therapies for victims with respiratory symptoms while assessments are underway. Inhaled bicarbonate and systemic or inhaled glucocorticoids also have been reported anecdotally to be beneficial. Chronic sequelae may include increased airways reactivity, which tends to diminish over time. Airways hyperreactivity may be more of a problem among those survivors that are older, have smoked, and/or have pre-existing chronic lung disease. Individuals suffering from irritant-induced asthma (IIA) due to workplace exposures to chlorine also tend to have similar characteristics, such as airways hyperresponsiveness to methacholine, and to be older and to have smoked. Other workplace studies, however, have indicated that workers exposed to chlorine dioxide/sulfur dioxide have tended to have increased risk for chronic bronchitis and/or recurrent wheezing attacks (one or more episodes) but not asthma, while those exposed to ozone have a greater incidence of asthma. Specific biomarkers for acute and chronic exposures to chlorine gas are currently lacking. Animal models for chlorine gas inhalation have demonstrated evidence of oxidative injury and inflammation. Early epithelial injury, airways hyperresponsiveness, and airway remodeling, likely diminishing over time, have been shown. As in humans, ALI/ARDS can occur, becoming more likely when the upper airways are bypassed. Inhalation models of chlorine toxicity provide unique opportunities for testing potential pharmacologic rescue agents." @default.
• W2040584700 created "2016-06-24" @default.
• W2040584700 creator A5020707125 @default.
• W2040584700 creator A5022260354 @default.
• W2040584700 date "2010-07-01" @default.
• W2040584700 modified "2023-10-14" @default.
• W2040584700 title "Chlorine Gas Inhalation: Human Clinical Evidence of Toxicity and Experience in Animal Models" @default.
• W2040584700 cites W1554855919 @default.
• W2040584700 cites W1737614241 @default.
• W2040584700 cites W1963495253 @default.
• W2040584700 cites W1969530790 @default.
• W2040584700 cites W1984001228 @default.
• W2040584700 cites W1993175010 @default.
• W2040584700 cites W2006630829 @default.
• W2040584700 cites W2032092394 @default.
• W2040584700 cites W2035698401 @default.
• W2040584700 cites W2037931181 @default.
• W2040584700 cites W2039269595 @default.
• W2040584700 cites W2045511520 @default.
• W2040584700 cites W2046434722 @default.
• W2040584700 cites W2049135121 @default.
• W2040584700 cites W2053144056 @default.
• W2040584700 cites W2053388673 @default.
• W2040584700 cites W2055640121 @default.
• W2040584700 cites W2061715939 @default.
• W2040584700 cites W2096372834 @default.
• W2040584700 cites W2105816994 @default.
• W2040584700 cites W2109256654 @default.
• W2040584700 cites W2110067602 @default.
• W2040584700 cites W2114561745 @default.
• W2040584700 cites W2123062776 @default.
• W2040584700 cites W2127791871 @default.
• W2040584700 cites W2132473599 @default.
• W2040584700 cites W2136027884 @default.
• W2040584700 cites W2137677922 @default.
• W2040584700 cites W2140953078 @default.
• W2040584700 cites W2146252604 @default.
• W2040584700 cites W2146560463 @default.
• W2040584700 cites W2163161393 @default.
• W2040584700 cites W2168124735 @default.
• W2040584700 cites W2168943823 @default.
• W2040584700 cites W2171848391 @default.
• W2040584700 cites W2178247938 @default.
• W2040584700 cites W2285827690 @default.
• W2040584700 cites W2300461977 @default.
• W2040584700 cites W2329522244 @default.
• W2040584700 cites W2037142666 @default.
• W2040584700 doi "https://doi.org/10.1513/pats.201001-008sm" @default.
• W2040584700 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3136961" @default.
• W2040584700 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20601629" @default.
• W2040584700 hasPublicationYear "2010" @default.
• W2040584700 type Work @default.
• W2040584700 sameAs 2040584700 @default.
• W2040584700 citedByCount "235" @default.
• W2040584700 countsByYear W20405847002012 @default.
• W2040584700 countsByYear W20405847002013 @default.
• W2040584700 countsByYear W20405847002014 @default.
• W2040584700 countsByYear W20405847002015 @default.
• W2040584700 countsByYear W20405847002016 @default.
• W2040584700 countsByYear W20405847002017 @default.
• W2040584700 countsByYear W20405847002018 @default.
• W2040584700 countsByYear W20405847002019 @default.
• W2040584700 countsByYear W20405847002020 @default.
• W2040584700 countsByYear W20405847002021 @default.
• W2040584700 countsByYear W20405847002022 @default.
• W2040584700 countsByYear W20405847002023 @default.
• W2040584700 crossrefType "journal-article" @default.
• W2040584700 hasAuthorship W2040584700A5020707125 @default.
• W2040584700 hasAuthorship W2040584700A5022260354 @default.
• W2040584700 hasBestOaLocation W20405847002 @default.
• W2040584700 hasConcept C105922876 @default.
• W2040584700 hasConcept C126322002 @default.
• W2040584700 hasConcept C141983124 @default.
• W2040584700 hasConcept C177713679 @default.
• W2040584700 hasConcept C2776042228 @default.
• W2040584700 hasConcept C2776178081 @default.
• W2040584700 hasConcept C2776238763 @default.
• W2040584700 hasConcept C2776348555 @default.
• W2040584700 hasConcept C2776779939 @default.
• W2040584700 hasConcept C2776954882 @default.
• W2040584700 hasConcept C2777714996 @default.
• W2040584700 hasConcept C2992694001 @default.
• W2040584700 hasConcept C42219234 @default.
• W2040584700 hasConcept C71924100 @default.
• W2040584700 hasConceptScore W2040584700C105922876 @default.
• W2040584700 hasConceptScore W2040584700C126322002 @default.
• W2040584700 hasConceptScore W2040584700C141983124 @default.
• W2040584700 hasConceptScore W2040584700C177713679 @default.
• W2040584700 hasConceptScore W2040584700C2776042228 @default.
• W2040584700 hasConceptScore W2040584700C2776178081 @default.
• W2040584700 hasConceptScore W2040584700C2776238763 @default.
• W2040584700 hasConceptScore W2040584700C2776348555 @default.
• W2040584700 hasConceptScore W2040584700C2776779939 @default.
• W2040584700 hasConceptScore W2040584700C2776954882 @default.
• W2040584700 hasConceptScore W2040584700C2777714996 @default.
• W2040584700 hasConceptScore W2040584700C2992694001 @default.
• W2040584700 hasConceptScore W2040584700C42219234 @default.
• W2040584700 hasConceptScore W2040584700C71924100 @default.

• next