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- W2040591847 abstract "<h3>Hypothesis</h3> There is an independent association between the different patterns of esophageal acid exposure in gastroesophageal reflux disease and the severity of the disease. <h3>Design</h3> Case-comparison study. <h3>Setting</h3> Department of surgery at a university hospital. <h3>Patients</h3> A group of 401 patients with increased esophageal acid exposure divided into 4 groups according to the pattern of reflux: postprandial (n=41), upright (n=74), supine (n=129), and bipositional (n=157). <h3>Main Outcome Measures</h3> The prevalence of mucosal injury and the status of the lower esophageal sphincter and esophageal motility were assessed in each group. <h3>Results</h3> The likelihood of having indicators of the severity of gastroesophageal reflux disease increases progressively from postprandial to upright, supine, and bipositional reflux. <h3>Conclusions</h3> The pattern of esophageal acid exposure in gastroesophageal reflux disease is an objective predictor of the severity of disease and could be used for therapeutic decisions." @default.
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- W2040591847 date "1999-08-01" @default.
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- W2040591847 title "The Pattern of Esophageal Acid Exposure in Gastroesophageal Reflux Disease Influences the Severity of the Disease" @default.
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- W2040591847 doi "https://doi.org/10.1001/archsurg.134.8.882" @default.
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