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• W2040602419 abstract "This histopathologic case-control study was designed to characterize the dynamic changes in protein expression of nuclear factor-kappa B (NF-kappaB)/p65 subunit, macrophage inflammatory protein-2 (MIP-2), and matrix metalloproteinase-9 (MMP-9) in postmortem brains of patients with and without intracerebral hemorrhage (ICH). Thirty-six human brains from patients with ICH and six control brains were included in this study. We found that expression levels of NF-kappaB/p65, MIP-2, and MMP-9 were each upregulated on the injured side of the hippocampus at times ranging from 2h to 5days post-ICH. Interestingly, the expression of all three markers was also upregulated on the uninjured side of the hippocampus and in the cerebellum, although to a lesser extent. These data suggest that inflammation occurs early and persists for several days after ICH in humans and could be involved in the progression of ICH-induced secondary brain damage." @default.
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• W2040602419 date "2010-06-01" @default.
• W2040602419 modified "2023-10-16" @default.
• W2040602419 title "Dynamic changes of inflammatory markers in brain after hemorrhagic stroke in humans: A postmortem study" @default.
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• W2040602419 doi "https://doi.org/10.1016/j.brainres.2010.04.033" @default.
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