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- W2040608325 abstract "Abstract Inositol 1,4,5-trisphosphate 3-kinase (IP3K) catalyzes the ATP-dependent phosphorylation of inositol 1,4,5-trisphosphate [Ins(1,4,5)P 3 ] generating inositol 1,3,4,5-tetrakisphosphate [Ins(1,3,4,5)P 4 ]. The inhibitory effects of all possible 38 regioisomers of inositol phosphates [InsPn] on the IP3K activity have been examined. The correlations between inhibitory potencies and their structural features allowed the assessment of the environment in the active site of IP3K, thus resulting in a proposed binding site model." @default.
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- W2040608325 date "1997-11-01" @default.
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- W2040608325 title "Molecular interactions of all possible regioisomers of synthetic myo-inositol phosphates with inositol 1,4,5-trisphosphate 3-kinase" @default.
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- W2040608325 doi "https://doi.org/10.1016/s0960-894x(97)10060-9" @default.
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