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- W2040652605 abstract "Domingo and colleagues, in this Journal, reported the increased incidence of Listeria meningitis in elderly amongst more recent cohorts. 1 Domingo P. Pomar V. Benito N. Coll P. The changing pattern of bacterial meningitis in adult patients at a large tertiary university hospital in Barcelona, Spain (1982-2010). J Infect. 2013; 66: 147-154 Abstract Full Text Full Text PDF PubMed Scopus (25) Google Scholar In ageing people, infections are not only more frequent compared to the younger population, but they also have a distinct epidemiological and clinical presentation, treatment and outcome. 2 High K.P. Bradley S.F. Gravenstein S. Mehr D.R. Quagliarello V.J. Richards C. et al. Clinical practice guideline for the evaluation of fever and infection in older adult residents of long-term care facilities: 2008 update by the infectious diseases society of America. J Am Geriatr Soc. 2009; 57: 375-394 Crossref PubMed Scopus (83) Google Scholar The aim of this prospective observational study was to evaluate, in patients aged over 50 years consecutively observed during a ten-year period at the ‘D. Cotugno’ hospital (Naples, Italy), the findings of Listeria meningitis and possibly distinguish its epidemiological, clinical and laboratory pictures from those of pneumococcal meningitis that is the most common form diagnosed in the elderly. The diagnosis of bacterial meningitis had to be based on the characteristic clinical signs and symptoms (i.e. fever, neck stiffness and impaired consciousness) and on cerebro-spinal fluid (CSF) pleocytosis (>10 cells/μL). The inclusion criteria were: i) diagnosis of pneumococcal or Listeria meningitis established by positive cultures and CSF pleocytosis; ii) age >50 years; iii) post-therapy follow-up of at least 8 weeks for surviving cases. The exclusion criterion was co-infection with HIV." @default.
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- W2040652605 date "2015-07-01" @default.
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- W2040652605 title "Listeria monocytogenes meningitis in the elderly: Distinctive characteristics of the clinical and laboratory presentation" @default.
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- W2040652605 doi "https://doi.org/10.1016/j.jinf.2015.02.003" @default.
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