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- W2040653140 abstract "Vitronectin receptor (alpha(V)beta(3)) antagonism has been implicated as a mechanism for the treatment of restenosis following balloon angioplasty. In this work we present results from screening of a focused combinatorial library based on a biphenyl moiety. Our SAR studies led to the identification of compounds with subnanomolar activity, selectivity towards the related GPIIbIIIa receptor and functional activity on human smooth muscle cell migration." @default.
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- W2040653140 date "2002-01-01" @default.
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- W2040653140 title "Biphenyls as potent vitronectin receptor antagonists" @default.
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- W2040653140 doi "https://doi.org/10.1016/s0960-894x(01)00717-x" @default.
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