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• W2040693513 abstract "delta-9-Tetrahydrocannabinol (THC) is a major psychoactive component of cannabis. We here studied, by quantitative in situ hybridization at the macroscopic level, the possible modulatory effects of acute THC (5 mg/kg/i.p.) on gene expression of the growth factor pleiotrophin (PTN) in the adult rat forebrain. We found, 30 min after a single injection of THC, a significant increase of PTN mRNA concentrations in the cingulate cortex (38%), fronto-parietal cortex (31%) and caudate-putamen (27%). In conclusion, this is the first report on THC regulation of growth factor gene expression in the brain." @default.
• W2040693513 created "2016-06-24" @default.
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• W2040693513 date "1994-07-01" @default.
• W2040693513 modified "2023-10-18" @default.
• W2040693513 title "Δ-9-Tetrahydrocannabinol regulates gene expression of the growth factor pleiotrophin in the forebrain" @default.
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• W2040693513 doi "https://doi.org/10.1016/0304-3940(94)91069-3" @default.
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