Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040694739> ?p ?o ?g. }
- W2040694739 endingPage "86" @default.
- W2040694739 startingPage "76" @default.
- W2040694739 abstract "Nitric oxide (NO) is a known modulator of angiogenesis. The NONOate subfamily of NO donors has long been used in experimental and clinical studies to promote angiogenesis. However, no studies have been conducted yet to compare the angiogenesis potential of these NO donors in respect to their pattern of NO release. We hypothesize that having different pattern of NO release, each of the NO donors in NONOate subfamily can promote key stages of angiogenesis in differential manner. To verify our hypothesis, NO donors with half life ranging from seconds to several hours and having very different pattern of NO release were selected to evaluate their efficacy in modulating angiogenesis. Endothelial tube formation using EAhy926 cells was maximally increased by Spermine NONOate (SP) treatment. SP treatment maximally induced both ex vivo and in vivo angiogenesis using egg yolk and cotton plug angiogenesis models respectively. Experiment using chick embryo partial ischemia model revealed SP as the best suited NO donor to recover ischemia driven hampered angiogenesis. The present study elaborated that differential release pattern of NO by different NO donors can modulate angiogenesis differentially and also suggested that SP have a unique pattern of NO release that best fits for angiogenesis." @default.
- W2040694739 created "2016-06-24" @default.
- W2040694739 creator A5005176596 @default.
- W2040694739 creator A5007230230 @default.
- W2040694739 creator A5011319687 @default.
- W2040694739 creator A5014876544 @default.
- W2040694739 creator A5029931153 @default.
- W2040694739 creator A5036738326 @default.
- W2040694739 creator A5043603281 @default.
- W2040694739 creator A5047256110 @default.
- W2040694739 creator A5050484942 @default.
- W2040694739 creator A5052382385 @default.
- W2040694739 creator A5055555139 @default.
- W2040694739 creator A5056412227 @default.
- W2040694739 creator A5057490217 @default.
- W2040694739 creator A5061044642 @default.
- W2040694739 creator A5067696537 @default.
- W2040694739 creator A5082373685 @default.
- W2040694739 creator A5090274656 @default.
- W2040694739 date "2014-01-01" @default.
- W2040694739 modified "2023-10-06" @default.
- W2040694739 title "A comparative study of NONOate based NO donors: Spermine NONOate is the best suited NO donor for angiogenesis" @default.
- W2040694739 cites W1966726553 @default.
- W2040694739 cites W1976390931 @default.
- W2040694739 cites W1976851726 @default.
- W2040694739 cites W1987269973 @default.
- W2040694739 cites W1989477788 @default.
- W2040694739 cites W2000738532 @default.
- W2040694739 cites W2001500938 @default.
- W2040694739 cites W2007737411 @default.
- W2040694739 cites W2012073884 @default.
- W2040694739 cites W2029216605 @default.
- W2040694739 cites W2036021417 @default.
- W2040694739 cites W2039972646 @default.
- W2040694739 cites W2041901511 @default.
- W2040694739 cites W2047647123 @default.
- W2040694739 cites W2063531974 @default.
- W2040694739 cites W2067543805 @default.
- W2040694739 cites W2077939517 @default.
- W2040694739 cites W2092145002 @default.
- W2040694739 cites W2096257801 @default.
- W2040694739 cites W2102823471 @default.
- W2040694739 cites W2106922430 @default.
- W2040694739 cites W2112251383 @default.
- W2040694739 cites W2120752600 @default.
- W2040694739 cites W2129282529 @default.
- W2040694739 cites W2133542546 @default.
- W2040694739 cites W2138291237 @default.
- W2040694739 cites W2138736529 @default.
- W2040694739 cites W2143260418 @default.
- W2040694739 cites W2144198949 @default.
- W2040694739 cites W2153726078 @default.
- W2040694739 cites W2156490538 @default.
- W2040694739 cites W2162147695 @default.
- W2040694739 cites W2168611216 @default.
- W2040694739 cites W2169381582 @default.
- W2040694739 cites W2318172046 @default.
- W2040694739 cites W2333366235 @default.
- W2040694739 cites W2338490942 @default.
- W2040694739 cites W4249809200 @default.
- W2040694739 cites W4254041558 @default.
- W2040694739 doi "https://doi.org/10.1016/j.niox.2013.12.002" @default.
- W2040694739 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24333563" @default.
- W2040694739 hasPublicationYear "2014" @default.
- W2040694739 type Work @default.
- W2040694739 sameAs 2040694739 @default.
- W2040694739 citedByCount "24" @default.
- W2040694739 countsByYear W20406947392014 @default.
- W2040694739 countsByYear W20406947392015 @default.
- W2040694739 countsByYear W20406947392016 @default.
- W2040694739 countsByYear W20406947392017 @default.
- W2040694739 countsByYear W20406947392018 @default.
- W2040694739 countsByYear W20406947392019 @default.
- W2040694739 countsByYear W20406947392020 @default.
- W2040694739 countsByYear W20406947392021 @default.
- W2040694739 countsByYear W20406947392022 @default.
- W2040694739 countsByYear W20406947392023 @default.
- W2040694739 crossrefType "journal-article" @default.
- W2040694739 hasAuthorship W2040694739A5005176596 @default.
- W2040694739 hasAuthorship W2040694739A5007230230 @default.
- W2040694739 hasAuthorship W2040694739A5011319687 @default.
- W2040694739 hasAuthorship W2040694739A5014876544 @default.
- W2040694739 hasAuthorship W2040694739A5029931153 @default.
- W2040694739 hasAuthorship W2040694739A5036738326 @default.
- W2040694739 hasAuthorship W2040694739A5043603281 @default.
- W2040694739 hasAuthorship W2040694739A5047256110 @default.
- W2040694739 hasAuthorship W2040694739A5050484942 @default.
- W2040694739 hasAuthorship W2040694739A5052382385 @default.
- W2040694739 hasAuthorship W2040694739A5055555139 @default.
- W2040694739 hasAuthorship W2040694739A5056412227 @default.
- W2040694739 hasAuthorship W2040694739A5057490217 @default.
- W2040694739 hasAuthorship W2040694739A5061044642 @default.
- W2040694739 hasAuthorship W2040694739A5067696537 @default.
- W2040694739 hasAuthorship W2040694739A5082373685 @default.
- W2040694739 hasAuthorship W2040694739A5090274656 @default.
- W2040694739 hasConcept C150903083 @default.
- W2040694739 hasConcept C185592680 @default.
- W2040694739 hasConcept C207001950 @default.