Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040702928> ?p ?o ?g. }
- W2040702928 endingPage "69" @default.
- W2040702928 startingPage "69" @default.
- W2040702928 abstract "Sodium fluoroacetate, commonly referred to as 1080, is a pesticide heavily used to control vertebrate pests. The development of tolerance to this poison by target species is a critical concern raised by its intensive use. Tolerance to 1080 is common amongst many native vertebrates in south-west Western Australia and is thought to be the result of a long period of coevolution with plant species that produce 1080 in their seeds and flowers. Among those vertebrate species tolerant to 1080 exposure is a subspecies of the tammar wallaby (Macropus eugenii). Tammars from Western Australia are tolerant while the subspecies present on Kangaroo Island is susceptible to 1080 exposure. The availability of genetic and genomic information, combined with a distinct difference in tolerance to 1080 between subspecies, makes the tammar wallaby an ideal species in which to study the genetic basis behind 1080 resistance. To date, research in this area has focussed on a candidate gene approach. Since 1080 inhibits the action of the mitochondrial aconitase enzyme, the aconitase gene ACO2 was considered a prime candidate for involvement in 1080 tolerance. However, sequencing of the full-length ACO2 transcript failed to identify a sequence variant between the two subspecies that would result in an amino acid change in the active site of the enzyme. Future studies will need to take a genome-wide approach to identify the gene(s) responsible for 1080 tolerance." @default.
- W2040702928 created "2016-06-24" @default.
- W2040702928 creator A5003786277 @default.
- W2040702928 creator A5019118793 @default.
- W2040702928 creator A5033708572 @default.
- W2040702928 creator A5041072212 @default.
- W2040702928 creator A5059662490 @default.
- W2040702928 creator A5067719457 @default.
- W2040702928 date "2013-01-01" @default.
- W2040702928 modified "2023-09-23" @default.
- W2040702928 title "Towards an understanding of the genetic basis behind 1080 (sodium fluoroacetate) tolerance and an investigation of the candidate gene ACO2" @default.
- W2040702928 cites W126684448 @default.
- W2040702928 cites W1480484298 @default.
- W2040702928 cites W1863727328 @default.
- W2040702928 cites W1965293008 @default.
- W2040702928 cites W1974143512 @default.
- W2040702928 cites W1979862336 @default.
- W2040702928 cites W1981175951 @default.
- W2040702928 cites W1984882211 @default.
- W2040702928 cites W1985078843 @default.
- W2040702928 cites W1997153406 @default.
- W2040702928 cites W2002912774 @default.
- W2040702928 cites W2009323305 @default.
- W2040702928 cites W2011431158 @default.
- W2040702928 cites W2016687627 @default.
- W2040702928 cites W2018035515 @default.
- W2040702928 cites W2027815063 @default.
- W2040702928 cites W2028717822 @default.
- W2040702928 cites W2054356926 @default.
- W2040702928 cites W2060222708 @default.
- W2040702928 cites W2065088243 @default.
- W2040702928 cites W2066409655 @default.
- W2040702928 cites W2067714729 @default.
- W2040702928 cites W2076471787 @default.
- W2040702928 cites W2093628092 @default.
- W2040702928 cites W2094497806 @default.
- W2040702928 cites W2101377652 @default.
- W2040702928 cites W2105513050 @default.
- W2040702928 cites W2116436591 @default.
- W2040702928 cites W2143780575 @default.
- W2040702928 cites W2147773320 @default.
- W2040702928 cites W2154883726 @default.
- W2040702928 cites W2155739395 @default.
- W2040702928 cites W2166764800 @default.
- W2040702928 cites W2312354675 @default.
- W2040702928 cites W2316983214 @default.
- W2040702928 cites W2321074978 @default.
- W2040702928 cites W2334816863 @default.
- W2040702928 cites W2341578320 @default.
- W2040702928 doi "https://doi.org/10.1071/zo12108" @default.
- W2040702928 hasPublicationYear "2013" @default.
- W2040702928 type Work @default.
- W2040702928 sameAs 2040702928 @default.
- W2040702928 citedByCount "5" @default.
- W2040702928 countsByYear W20407029282013 @default.
- W2040702928 countsByYear W20407029282014 @default.
- W2040702928 countsByYear W20407029282015 @default.
- W2040702928 countsByYear W20407029282020 @default.
- W2040702928 countsByYear W20407029282021 @default.
- W2040702928 crossrefType "journal-article" @default.
- W2040702928 hasAuthorship W2040702928A5003786277 @default.
- W2040702928 hasAuthorship W2040702928A5019118793 @default.
- W2040702928 hasAuthorship W2040702928A5033708572 @default.
- W2040702928 hasAuthorship W2040702928A5041072212 @default.
- W2040702928 hasAuthorship W2040702928A5059662490 @default.
- W2040702928 hasAuthorship W2040702928A5067719457 @default.
- W2040702928 hasBestOaLocation W20407029282 @default.
- W2040702928 hasConcept C104317684 @default.
- W2040702928 hasConcept C17966761 @default.
- W2040702928 hasConcept C200886947 @default.
- W2040702928 hasConcept C2777042810 @default.
- W2040702928 hasConcept C2779970363 @default.
- W2040702928 hasConcept C28859421 @default.
- W2040702928 hasConcept C2910561697 @default.
- W2040702928 hasConcept C54355233 @default.
- W2040702928 hasConcept C69991583 @default.
- W2040702928 hasConcept C78458016 @default.
- W2040702928 hasConcept C86803240 @default.
- W2040702928 hasConcept C90856448 @default.
- W2040702928 hasConceptScore W2040702928C104317684 @default.
- W2040702928 hasConceptScore W2040702928C17966761 @default.
- W2040702928 hasConceptScore W2040702928C200886947 @default.
- W2040702928 hasConceptScore W2040702928C2777042810 @default.
- W2040702928 hasConceptScore W2040702928C2779970363 @default.
- W2040702928 hasConceptScore W2040702928C28859421 @default.
- W2040702928 hasConceptScore W2040702928C2910561697 @default.
- W2040702928 hasConceptScore W2040702928C54355233 @default.
- W2040702928 hasConceptScore W2040702928C69991583 @default.
- W2040702928 hasConceptScore W2040702928C78458016 @default.
- W2040702928 hasConceptScore W2040702928C86803240 @default.
- W2040702928 hasConceptScore W2040702928C90856448 @default.
- W2040702928 hasIssue "1" @default.
- W2040702928 hasLocation W20407029281 @default.
- W2040702928 hasLocation W20407029282 @default.
- W2040702928 hasOpenAccess W2040702928 @default.
- W2040702928 hasPrimaryLocation W20407029281 @default.
- W2040702928 hasRelatedWork W1965641268 @default.
- W2040702928 hasRelatedWork W2014531639 @default.