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• W2040705247 abstract "Article1 July 1965Pericholangitis and Ulcerative ColitisII. Clinical AspectsS. P. MISTILIS, M.B., A. P. SKYRING, M.B., M.R.A.C.P., S. J. M. GOULSTON, M.B., F.R.C.P., F.R.A.C.P.S. P. MISTILIS, M.B.Search for more papers by this author, A. P. SKYRING, M.B., M.R.A.C.P.Search for more papers by this author, S. J. M. GOULSTON, M.B., F.R.C.P., F.R.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-1-17 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPericholangitis associated with cases of ulcerative colitis has been recognized in the past (1-5), but the exact incidence and clinical importance of this lesion has not been clearly defined. Information regarding relative frequency, the clinical features and course, the exact relationship to the colonic lesion, the incidence of cirrhosis and portal hypertension, and the relationship of this disease to biliary cirrhosis is not available in the literature. This is in part due to the small number of documented cases and the absence of long-term studies with sequential liver biopsies.In this study patients with ulcerative colitis in whom pericholangitis was...References1. KLECKNERSTAUFFERBARGENDOCKERTY MSMHJAMB: Hepatic lesions in the living patient with chronic ulcerative colitis as demonstrated by needle biopsy. Gastroenterology 22: 13, 1952. CrossrefMedlineGoogle Scholar2. BODENRANKINGOULSTONMORROW RWJGSJW: The liver in ulcerative colitis: the significance of raised serum alkaline phosphatase levels. Lancet 2: 245, 1959. CrossrefMedlineGoogle Scholar3. VINNICKKERNCORLEY IEFWD: Serum 5-nucleotidase and pericholangitis in patients with chronic ulcerative colitis. Gastroenterology 45: 492, 1963. CrossrefMedlineGoogle Scholar4. KlMMELSTIELLARGEVERNER PHLHD: Liver damage in ulcerative colitis. Amer. J. Path. 28: 259, 1952. MedlineGoogle Scholar5. RANKINBODENGOULSTONMORROW JGRWSJW: The liver in ulcerative colitis: treatment of pericholangitis with tetracycline. Lancet 2: 1110, 1959. CrossrefMedlineGoogle Scholar6. MISTILIS SP: Pericholangitis and ulcerative colitis: I. Pathology, etiology, and pathogenesis. Ann. Intern. Med. 63: 1, 1965. LinkGoogle Scholar7. MISTILISGOULSTON SPSJ: Liver disease in ulcerative colitis, in Recent Advances in Gastroenterology, edited by BROOKE, B. N. Churchill, London, 1965. In press. Google Scholar8. ROSSSWARTZ JRJM: Hepatic dysfunction and cirrhosis in chronic ulcerative colitis. Gastroenterology 10: 81, 1948. MedlineGoogle Scholar9. POLLARDBLOCK HMM: Association of hepatic insufficiency with chronic ulcerative colitis. Arch. Intern. Med. (Chicago) 82: 159, 1948. CrossrefGoogle Scholar10. KANINLEVINLIN DERF HJJJMC: The association of liver disease with ulcerative colitis. Amer. J. Gastroent. 25: 172, 1956. MedlineGoogle Scholar11. BENDANDI A: Liver function in ulcerative colitis. Gastroenterologia (Basel) 86: 658, 1956. CrossrefMedlineGoogle Scholar12. JONESBAGENSTOSSBARGEN GWAHJA: Hepatic lesions and dysfunction associated with chronic ulcerative colitis. Amer. J. Med. Sci. 221: 279, 1951. CrossrefMedlineGoogle Scholar13. MONTO AS: The liver in ulcerative disorders of the small intestine. Ann. Intern. Med. 50: 1385, 1959. LinkGoogle Scholar14. LANGERCRANTZWINBERGZETTERSTROM JJR: Extracolonic manifestations in chronic ulcerative colitis. Acta Paediat. (Stockholm) 47: 675, 1958. CrossrefMedlineGoogle Scholar15. MACMAHONTHANNHAUSER HESJ: Xanthomatous biliary cirrhosis (a clinical syndrome). Ann. Intern. Med. 30: 121, 1949. LinkGoogle Scholar16. MACMAHON HE: Biliary cirrhosis. Differential features of the five types. Lab. Invest. 4: 243, 1955. MedlineGoogle Scholar17. AHRENSPAYNEKUNKELEISENMENGERBLONDHEIM EHMAHGWJSH: Primary biliary cirrhosis. Medicine (Balt.) 29: 299, 1950. CrossrefMedlineGoogle Scholar18. SHERLOCK S: Primary biliary cirrhosis (chronic intrahepatic obstructive jaundice). Gastroenterology 37: 574, 1959. CrossrefMedlineGoogle Scholar19. STEINFELDDAVIDSONGORDONGREEN JLJDRSFE: The mechanism of hypoproteinaemia in patients with regional enteritis and ulcerative colitis. Amer. J. Med. 29: 405, 1960. CrossrefMedlineGoogle Scholar20. MISTLISSKYRINGGOULSTON SPAPSJ: Effect of long term tetracycline, steroid therapy, colectomy and biliary drainage in pericholangitis associated with ulcerative colitis. Submitted for publication. Google Scholar21. MCCARTHYREAD CFAE: Bleeding esophageal varices in ulcerative colitis. Gastroenterology 42: 325, 1962. CrossrefGoogle Scholar22. OLHAGEN L: Ulcerative colitis in cirrhosis of the liver. Acta Med. Scand. 162: 143, 1958. CrossrefMedlineGoogle Scholar23. RANKINBLACKBURN JGCR: Portal hypertension in ulcerative colitis. Submitted for publication. Google Scholar24. SHERLOCK S: Diseases of the liver and biliary system. Blackwell Scientific Publications, 1963. Google Scholar25. VINNICKKERN IEF: Liver diseases in ulcerative colitis. Arch. Intern. Med. (Chicago) 112: 41, 1963. CrossrefMedlineGoogle Scholar26. BAGGENSTOSS AH: Post necrotic cirrhosis: morphology, etiology and pathogenesis, in Progress in Liver Disease, edited by POPPER, H., SCHAFFNER, F. Grune & Stratton, New York, 1961. Google Scholar27. TUMENMONAGHANJOBB HJJFE: Hepatic cirrhosis as a complication of chronic ulcerative colitis. Ann. Intern. Med. 26: 542, 1947. LinkGoogle Scholar28. BARGEN JA: Diseases of the liver associated with ulcerative colitis. Ann. Intern. Med. 39: 285, 1953. LinkGoogle Scholar29. VINNICKKERN IEF: Biliary cirrhosis in a patient with chronic ulcerative colitis. Gastroenterology 45: 529, 1963. CrossrefMedlineGoogle Scholar30. PARKERKENDALL RGEJ: The liver in ulcerative colitis. Brit. Med. J. 2: 1030, 1954. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Sydney,From The A. W. Morrow Department of Gastroenterology, Royal Prince Alfred Hospital, Sydney, Australia.This study was supported by a grant from the Bushell Trust, Sydney, Australia.Requests for reprints should be addressed to Dr. Steven P. Mistilis, Parke Davis Senior Research Fellow, The A. W. Morrow Department of Gastroenterology, Royal Prince Alfred Hospital, Sydney, N.S.W., Australia. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUlcerative ColitisOverview: Liver disease and transplantationSteroid-Responsive (Autoimmune?) 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Pathology, Etiology, and PathogenesisSTEVEN P. MISTILIS, M.B.B.S. 1 July 1965Volume 63, Issue 1Page: 17-26KeywordsCirrhosisColitisHypertensionLesionsLiverPhosphatasesPortal hypertensionProteinsUlcerative colitisZinc Issue Published: 1 July 1965 PDF downloadLoading ..." @default.
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