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• W2040713034 endingPage "37" @default.
• W2040713034 startingPage "29" @default.
• W2040713034 abstract "The 1,3-dipolar cycloaddition of azomethine ylides generated in situ from the reaction of isatins or acenaphthylene-1,2-dione and 1,3-thiazolane-4-carboxylic acid to various exocyclic dipolarophiles synthesized from estrone afforded a library of novel C-16 spiro oxindole or acenaphthylene-1-one – 7-(aryl)tetrahydro-1H-pyrrolo[1,2-c][1,3]thiazole – estrone hybrid heterocycles. These reactions occur regio- and stereo-selectively affording a single isomer of the spiro estrones in excellent yields with the formation of two C–C and one C–N bonds along with the generation of four new contiguous stereo-centers in a single step." @default.
• W2040713034 created "2016-06-24" @default.
• W2040713034 creator A5037081798 @default.
• W2040713034 creator A5070691128 @default.
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• W2040713034 date "2014-04-01" @default.
• W2040713034 modified "2023-10-18" @default.
• W2040713034 title "Synthesis of novel 16-spiro steroids: 7-(Aryl)tetrahydro-1H-pyrrolo[1,2-c][1,3]thiazolo estrone hybrid heterocycles" @default.
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• W2040713034 doi "https://doi.org/10.1016/j.steroids.2014.01.003" @default.
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