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• W2040716172 abstract "The new fMLF analogues 1-4, incorporating chimeric S-proline-methionine residues (namely the homochiral cis-4(S)-methylthio-(S)-proline (10) and the heterochiral trans-4(R)-methylthio-(S)-proline) (17) in place of the native S-methionine, have been prepared; their solution conformation and activity as agonists or antagonists of formylpeptide receptors have been studied. In addition to peptides 1-4, which maintain the Met gamma-thiomethyl-ether function, the analogues Boc-PLF-OMe (18) and For-PLF-OMe (19) devoid, as compared with 1-4, of position 1 side chain, have been synthesized and their activity examined." @default.
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• W2040716172 date "2006-04-01" @default.
• W2040716172 modified "2023-10-10" @default.
• W2040716172 title "Chemotactic peptides: fMLF-OMe analogues incorporating proline–methionine chimeras as N-terminal residue" @default.
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• W2040716172 doi "https://doi.org/10.1016/j.bmc.2005.11.001" @default.
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