Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040748781> ?p ?o ?g. }
- W2040748781 endingPage "711" @default.
- W2040748781 startingPage "699" @default.
- W2040748781 abstract "We studied the cytological and biochemical properties of the FtsA protein of Streptococcus pneumoniae. FtsA is a widespread bacterial cell division protein that belongs to the actin superfamily. In Escherichia coli and Bacillus subtilis, FtsA localizes to the septal ring after FtsZ, but its exact role in septation is not known. In S. pneumoniae, we found that, during exponential growth, the protein localizes to the nascent septa, at the equatorial zones of the dividing cells, where an average of 2200 FtsA molecules per cell are present. Likewise, FtsZ was found to localize with the same pattern and to be present at an average of 3000 molecules per cell. Consistent with the colocalization, FtsA was found to interact with FtsZ and with itself. Purified FtsA is able to bind several nucleotides, the affinity being highest for adenosine triphosphate (ATP), and lower for other triphosphates and diphosphates. The protein polymerizes in vitro, in a nucleotide-dependent manner, forming long corkscrew-like helixes, composed of 2 + 2 paired protofilaments. No nucleotide hydrolytic activity was detected. Consistent with the absence of an ATPase activity, the polymers are highly stable and not dynamic. These results suggest that the FtsA protein could also polymerize in vivo and the polymers participate in septation." @default.
- W2040748781 created "2016-06-24" @default.
- W2040748781 creator A5006627107 @default.
- W2040748781 creator A5015340992 @default.
- W2040748781 creator A5024970618 @default.
- W2040748781 creator A5038746248 @default.
- W2040748781 creator A5062472986 @default.
- W2040748781 creator A5063068804 @default.
- W2040748781 creator A5069138882 @default.
- W2040748781 creator A5088907700 @default.
- W2040748781 creator A5089169608 @default.
- W2040748781 date "2004-12-02" @default.
- W2040748781 modified "2023-10-13" @default.
- W2040748781 title "Cell division in cocci: localization and properties of the Streptococcus pneumoniae FtsA protein" @default.
- W2040748781 cites W1020194079 @default.
- W2040748781 cites W1446111646 @default.
- W2040748781 cites W1498555668 @default.
- W2040748781 cites W1630044161 @default.
- W2040748781 cites W1674853673 @default.
- W2040748781 cites W1713883573 @default.
- W2040748781 cites W1757236696 @default.
- W2040748781 cites W1822679997 @default.
- W2040748781 cites W1835785043 @default.
- W2040748781 cites W1841538792 @default.
- W2040748781 cites W1898425151 @default.
- W2040748781 cites W1946075442 @default.
- W2040748781 cites W194865955 @default.
- W2040748781 cites W1975317507 @default.
- W2040748781 cites W1983231244 @default.
- W2040748781 cites W1984150901 @default.
- W2040748781 cites W1991609657 @default.
- W2040748781 cites W1999746361 @default.
- W2040748781 cites W2000707426 @default.
- W2040748781 cites W2003527847 @default.
- W2040748781 cites W2019026718 @default.
- W2040748781 cites W2023706157 @default.
- W2040748781 cites W2028905487 @default.
- W2040748781 cites W2039622251 @default.
- W2040748781 cites W2045934295 @default.
- W2040748781 cites W2050097692 @default.
- W2040748781 cites W2051306574 @default.
- W2040748781 cites W2052744361 @default.
- W2040748781 cites W2060221814 @default.
- W2040748781 cites W2078463542 @default.
- W2040748781 cites W2080263535 @default.
- W2040748781 cites W2083026006 @default.
- W2040748781 cites W2091393253 @default.
- W2040748781 cites W2093136988 @default.
- W2040748781 cites W2099299706 @default.
- W2040748781 cites W2099542485 @default.
- W2040748781 cites W2100403047 @default.
- W2040748781 cites W2111551045 @default.
- W2040748781 cites W2115004879 @default.
- W2040748781 cites W2120004588 @default.
- W2040748781 cites W2120007451 @default.
- W2040748781 cites W2122259563 @default.
- W2040748781 cites W2124738341 @default.
- W2040748781 cites W2128000228 @default.
- W2040748781 cites W2130108891 @default.
- W2040748781 cites W2143047507 @default.
- W2040748781 cites W2164045264 @default.
- W2040748781 cites W2172147965 @default.
- W2040748781 cites W2175157633 @default.
- W2040748781 cites W221248817 @default.
- W2040748781 cites W300581886 @default.
- W2040748781 cites W61355124 @default.
- W2040748781 doi "https://doi.org/10.1111/j.1365-2958.2004.04432.x" @default.
- W2040748781 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15660997" @default.
- W2040748781 hasPublicationYear "2004" @default.
- W2040748781 type Work @default.
- W2040748781 sameAs 2040748781 @default.
- W2040748781 citedByCount "116" @default.
- W2040748781 countsByYear W20407487812012 @default.
- W2040748781 countsByYear W20407487812013 @default.
- W2040748781 countsByYear W20407487812014 @default.
- W2040748781 countsByYear W20407487812015 @default.
- W2040748781 countsByYear W20407487812016 @default.
- W2040748781 countsByYear W20407487812017 @default.
- W2040748781 countsByYear W20407487812018 @default.
- W2040748781 countsByYear W20407487812019 @default.
- W2040748781 countsByYear W20407487812020 @default.
- W2040748781 countsByYear W20407487812021 @default.
- W2040748781 countsByYear W20407487812022 @default.
- W2040748781 countsByYear W20407487812023 @default.
- W2040748781 crossrefType "journal-article" @default.
- W2040748781 hasAuthorship W2040748781A5006627107 @default.
- W2040748781 hasAuthorship W2040748781A5015340992 @default.
- W2040748781 hasAuthorship W2040748781A5024970618 @default.
- W2040748781 hasAuthorship W2040748781A5038746248 @default.
- W2040748781 hasAuthorship W2040748781A5062472986 @default.
- W2040748781 hasAuthorship W2040748781A5063068804 @default.
- W2040748781 hasAuthorship W2040748781A5069138882 @default.
- W2040748781 hasAuthorship W2040748781A5088907700 @default.
- W2040748781 hasAuthorship W2040748781A5089169608 @default.
- W2040748781 hasBestOaLocation W20407487811 @default.
- W2040748781 hasConcept C104317684 @default.
- W2040748781 hasConcept C12554922 @default.
- W2040748781 hasConcept C125705527 @default.